To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Peter Choi, Department of Anesthesia, Vancouver Hospital, University of British Columbia, Vancouver, British Columbia, Canada,
J Mark Ansermino, Department of Pediatric Anesthesia, British Columbia Children's Hospital, Vancouver, British Columbia, Canada
The use of intravenous (IV) fluids for volume resuscitation and fluid replacement in the surgical or critically ill patient has been studied and practiced for nearly 90 years. Four systematic reviews have pooled data from randomised controlled trials (RCTs) comparing isotonic crystalloids to colloids in clinically heterogeneous populations. Human albumin has received the most attention and controversy amongst IV fluids. Amongst patients with penetrating injuries requiring surgery, initial fluid resuscitation with hypertonic saline dextran (HSD), compared with isotonic crystalloids, appears to increase the survival rate to hospital discharge. A large number of RCTs have been conducted in the field of fluid therapy; however, most of them have been small and not powered to detect differences in clinical outcomes. The publication of the Saline versus Albumin Fluid Evaluation (SAFE) Study has demonstrated the feasibility of conducting large multicentre RCTs to answer questions on fluid therapy.
Email your librarian or administrator to recommend adding this to your organisation's collection.