Townsend's attached-eddy hypothesis (AEH) provides a theoretical description of turbulence statistics in the logarithmic region in terms of coherent motions that are self-similar with the wall-normal distance ($y$). This hypothesis was further extended by Perry and coworkers who proposed attached-eddy models that predict the coexistence of the logarithmic law in the mean velocity and streamwise turbulence intensity as well as spectral scaling for the streamwise energy spectra. The AEH can be used to predict the statistical behaviours of wall turbulence, yet revealing such behaviours has remained an elusive task because the proposed description is established within the limits of asymptotically high Reynolds numbers. Here, we show the self-similar behaviour of turbulence motions contained within wall-attached structures of streamwise velocity fluctuations using the direct numerical simulation dataset of turbulent boundary layer, channel, and pipe flows ($Re_{\tau } \approx 1000$). The physical sizes of the identified structures are geometrically self-similar in terms of height, and the associated turbulence intensity follows the logarithmic variation in all three flows. Moreover, the corresponding two-dimensional energy spectra are aligned along a linear relationship between the streamwise and spanwise wavelengths ($\lambda _x$ and $\lambda _z$, respectively) in the large-scale range ($12y < \lambda _x <3\text{--}4\delta$), which is reminiscent of self-similarity. Consequently, one-dimensional spectra obtained by integrating the two-dimensional spectra over the self-similar range show some evidence for self-similar scaling $\lambda _x \sim \lambda _z$ and the possible existence of $k_x^{-1}$ and $k_z^{-1}$ scaling regions in a similar subrange. The present results reveal that the asymptotic behaviours can be obtained by identifying the self-similar coherent structures in canonical wall turbulence, albeit in low-Reynolds-number flows.

The three-dimensional clusters of streamwise velocity fluctuations ($u$) in turbulent boundary layers (TBLs) are explored from the perspective of the attached-eddy model, which provides a basis for understanding the asymptotic behaviours of high-Reynolds-number wall turbulence in terms of coherent structures. We extract the $u$ clusters from the direct numerical simulation data of a TBL subjected to an adverse pressure gradient ($\unicode[STIX]{x1D6FD}=1.43$). For comparison, the direct numerical simulation data of a zero-pressure-gradient TBL are included. The identified structures are decomposed into attached self-similar, attached non-self-similar, detached self-similar and detached non-self-similar motions with respect to the minimum distance from the wall ($y_{min}$) and height ($l_{y}$). The attached structures ($y_{min}\approx 0$) are the main energy-containing motions and carry approximately half of the streamwise Reynolds stress and the Reynolds shear stress in the logarithmic and outer regions. The sizes of the attached self-similar structures scale with $l_{y}$, and their population density has an inverse-scale distribution over the range $0.4\unicode[STIX]{x1D6FF}<l_{y}<0.58\unicode[STIX]{x1D6FF}$ ($\unicode[STIX]{x1D6FF}$ is the 99 % boundary layer thickness). They also contribute to the logarithmic variation of the streamwise Reynolds stress and to the presence of the $k_{z}^{-1}$ region in the pre-multiplied energy spectra ($k_{z}$ is the spanwise wavenumber), i.e. these structures are universal wall motions in the logarithmic region. The tall attached structures with $l_{y}=O(\unicode[STIX]{x1D6FF})$ are non-self-similar and responsible for the enhancement of the outer large scales under the adverse pressure gradient. They extend beyond $6\unicode[STIX]{x1D6FF}$ in the streamwise direction and penetrate deeply into the near-wall region, which is reminiscent of very-large-scale motions or superstructures. The detached self-similar structures ($y_{min}>0$ and $l_{y}>100\unicode[STIX]{x1D708}/u_{\unicode[STIX]{x1D70F}}$) are geometrically isotropic and mainly arise in the outer region, whereas the sizes of the detached non-self-similar structures ($y_{min}>0$ and $l_{y}<100\unicode[STIX]{x1D708}/u_{\unicode[STIX]{x1D70F}}$) scale with the Kolmogorov length scale. Here, $\unicode[STIX]{x1D708}$ is the kinematic viscosity and $u_{\unicode[STIX]{x1D70F}}$ the friction velocity. The present study provides a new perspective on the analysis of turbulence structures in the view of the attached-eddy model.

The COllaborative project of Development of Anthropometrical measures in Twins (CODATwins) project is a large international collaborative effort to analyze individual-level phenotype data from twins in multiple cohorts from different environments. The main objective is to study factors that modify genetic and environmental variation of height, body mass index (BMI, kg/m2) and size at birth, and additionally to address other research questions such as long-term consequences of birth size. The project started in 2013 and is open to all twin projects in the world having height and weight measures on twins with information on zygosity. Thus far, 54 twin projects from 24 countries have provided individual-level data. The CODATwins database includes 489,981 twin individuals (228,635 complete twin pairs). Since many twin cohorts have collected longitudinal data, there is a total of 1,049,785 height and weight observations. For many cohorts, we also have information on birth weight and length, own smoking behavior and own or parental education. We found that the heritability estimates of height and BMI systematically changed from infancy to old age. Remarkably, only minor differences in the heritability estimates were found across cultural–geographic regions, measurement time and birth cohort for height and BMI. In addition to genetic epidemiological studies, we looked at associations of height and BMI with education, birth weight and smoking status. Within-family analyses examined differences within same-sex and opposite-sex dizygotic twins in birth size and later development. The CODATwins project demonstrates the feasibility and value of international collaboration to address gene-by-exposure interactions that require large sample sizes and address the effects of different exposures across time, geographical regions and socioeconomic status.

Cable-driven parallel robots (CDPRs) possess a lot of advantages over conventional parallel manipulators and link-based robot manipulators in terms of acceleration due to their low inertia. This paper deals with under-constrained CDPRs, which manipulate the end-effector to carrying the payload by using a number of cables less than six, often used preferably owing to their simple structures. Since a smaller number of cables than six are used, the end-effector of CDPR has uncontrollable degrees of freedom and that causes swaying motion and oscillations. In this paper, a scheme to curb on the unwanted oscillation of the end-effector of the CDPR with three cables is proposed based on multimode input shaping. The precise dynamic model of the under-constrained CDPR is obtained to find natural frequencies, which depends on the position of the end-effector. The advantage of the proposed method is that it is practicable to generate the trajectories for vibration suppression based on multi-mode input-shaping scheme in spite of the complexity in the dynamics and the difficulty in computing the natural frequencies of the CDPR, which are required in any input-shaping scheme. To prove the effectiveness of the proposed method, computer simulations and experiments were carried out by using 3-D motion for CDPR with three cables.

Wall turbulence is a ubiquitous phenomenon in nature and engineering applications, yet predicting such turbulence is difficult due to its complexity. High-Reynolds-number turbulence arises in most practical flows, and is particularly complicated because of its wide range of scales. Although the attached-eddy hypothesis postulated by Townsend can be used to predict turbulence intensities and serves as a unified theory for the asymptotic behaviours of turbulence, the presence of coherent structures that contribute to the logarithmic behaviours has not been observed in instantaneous flow fields. Here, we demonstrate the logarithmic region of the turbulence intensity by identifying wall-attached structures of the velocity fluctuations ($u_{i}$) through the direct numerical simulation of a moderate-Reynolds-number boundary layer ($Re_{\unicode[STIX]{x1D70F}}\approx 1000$). The wall-attached structures are self-similar with respect to their heights ($l_{y}$), and in particular the population density of the streamwise component ($u$) scales inversely with $l_{y}$, reminiscent of the hierarchy of attached eddies. The turbulence intensities contained within the wall-parallel components ($u$ and $w$) exhibit the logarithmic behaviour. The tall attached structures ($l_{y}^{+}>100$) of $u$ are composed of multiple uniform momentum zones (UMZs) with long streamwise extents, whereas those of the cross-stream components ($v$ and $w$) are relatively short with a comparable width, suggesting the presence of tall vortical structures associated with multiple UMZs. The magnitude of the near-wall peak observed in the streamwise turbulent intensity increases with increasing $l_{y}$, reflecting the nested hierarchies of the attached $u$ structures. These findings suggest that the identified structures are prime candidates for Townsend’s attached-eddy hypothesis and that they can serve as cornerstones for understanding the multiscale phenomena of high-Reynolds-number boundary layers.

Direct numerical simulation of a turbulent boundary layer (TBL) subjected to a moderate adverse pressure gradient (APG, $\unicode[STIX]{x1D6FD}=1.45$) is performed to explore the contribution of large scales to the skin friction, where $\unicode[STIX]{x1D6FD}$ is the Clauser pressure gradient parameter. The Reynolds number based on the momentum thickness develops from $Re_{\unicode[STIX]{x1D703}}\approx 110$ to 6000 with an equilibrium region in $Re_{\unicode[STIX]{x1D703}}=4000$–5500. The spanwise wavelength ($\unicode[STIX]{x1D706}_{z}$) spectra of the streamwise and spanwise velocity fluctuations show that the large-scale energy is significantly enhanced throughout the boundary layer. We quantify the superposition and amplitude modulation effects of these enhanced large scales on the skin friction coefficient ($C_{f}$) by employing two approaches: (i) spanwise co-spectra of $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ and $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$; (ii) conditionally averaged $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ and $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$. The velocity–vorticity correlations $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ and $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$ are related to the advective transport and the vortex stretching, respectively. Although $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ negatively contributes to $C_{f}$, the positive contribution of the large scales ($\unicode[STIX]{x1D706}_{z}>0.5\unicode[STIX]{x1D6FF}$) is observed in the co-spectra of weighted $\langle v\unicode[STIX]{x1D714}_{z}\rangle$. For the co-spectra of weighted $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$, we observe an outer peak at $\unicode[STIX]{x1D706}_{z}\approx 0.75\unicode[STIX]{x1D6FF}$ and the superposition of the large scales in the buffer region, leading to the enhancement of $C_{f}$. The magnitude of $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ and $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$ depends on the large-scale streamwise velocity fluctuations ($u_{L}$). In particular, the negative-$u_{L}$ events amplify $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ in the outer region, and $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$ is enhanced by the positive-$u_{L}$ events. As a result, the skin friction induced by $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ and $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$ increases in the present APG TBL.

It has often been proposed that the formation of large-scale motion (or bulges) is a consequence of successive mergers and/or growth of near-wall hairpin vortices. In the present study, we report our direct observation that large-scale motion is generated by an instability of an ‘amplified’ streaky motion in the outer region (i.e. very-large-scale motion). We design a numerical experiment in turbulent channel flow up to $Re_{\unicode[STIX]{x1D70F}}\simeq 2000$ where a streamwise-uniform streaky motion is artificially driven by body forcing in the outer region computed from the previous linear theory (Hwang & Cossu, J. Fluid Mech., vol. 664, 2015, pp. 51–73). As the forcing amplitude is increased, it is found that an energetic streamwise vortical structure emerges at a streamwise wavelength of $\unicode[STIX]{x1D706}_{x}/h\simeq 1{-}5$ ($h$ is the half-height of the channel). The application of dynamic mode decomposition and the examination of turbulence statistics reveal that this structure is a consequence of the sinuous-mode instability of the streak, a subprocess of the self-sustaining mechanism of the large-scale outer structures. It is also found that the statistical features of the vortical structure are remarkably similar to those of the large-scale motion in the outer region. Finally, it is proposed that the largest streamwise length of the streak instability determines the streamwise length scale of very-large-scale motion.

Whether monozygotic (MZ) and dizygotic (DZ) twins differ from each other in a variety of phenotypes is important for genetic twin modeling and for inferences made from twin studies in general. We analyzed whether there were differences in individual, maternal and paternal education between MZ and DZ twins in a large pooled dataset. Information was gathered on individual education for 218,362 adult twins from 27 twin cohorts (53% females; 39% MZ twins), and on maternal and paternal education for 147,315 and 143,056 twins respectively, from 28 twin cohorts (52% females; 38% MZ twins). Together, we had information on individual or parental education from 42 twin cohorts representing 19 countries. The original education classifications were transformed to education years and analyzed using linear regression models. Overall, MZ males had 0.26 (95% CI [0.21, 0.31]) years and MZ females 0.17 (95% CI [0.12, 0.21]) years longer education than DZ twins. The zygosity difference became smaller in more recent birth cohorts for both males and females. Parental education was somewhat longer for fathers of DZ twins in cohorts born in 1990–1999 (0.16 years, 95% CI [0.08, 0.25]) and 2000 or later (0.11 years, 95% CI [0.00, 0.22]), compared with fathers of MZ twins. The results show that the years of both individual and parental education are largely similar in MZ and DZ twins. We suggest that the socio-economic differences between MZ and DZ twins are so small that inferences based upon genetic modeling of twin data are not affected.

Direct numerical simulation data of a turbulent boundary layer ($Re_{\unicode[STIX]{x1D70F}}=1000$) were used to investigate the large-scale influences on the vortical structures that contribute to the local skin friction. The amplitudes of the streamwise and wall-normal swirling strengths ($\unicode[STIX]{x1D706}_{x}$ and $\unicode[STIX]{x1D706}_{y}$) were conditionally sampled by measuring the large-scale streamwise velocity fluctuations ($u_{l}$). In the near-wall region, the amplitudes of $\unicode[STIX]{x1D706}_{x}$ and $\unicode[STIX]{x1D706}_{y}$ decreased under negative $u_{l}$ rather than under positive $u_{l}$. This behaviour arose from the spanwise motions within the footprints of the large-scale low-speed ($u_{l}<0$) and high-speed structures ($u_{l}>0$). The intense spanwise motions under the footprint of positive $u_{l}$ noticeably strengthened the small-scale spanwise velocity fluctuations ($w_{s}$) below the centre of the near-wall vortical structures as compared to $w_{s}$ within the footprint of negative $u_{l}$. The streamwise and wall-normal components were attenuated or amplified around the modulated vortical motions, which in turn led to the dependence of the swirling strength on the $u_{l}$ event. We quantified the contribution of the modulated vortical motions $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$, which were related to a change-of-scale effect due to the vortex-stretching force, to the local skin friction. In the near-wall region, intense values of $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$ were observed for positive $u_{l}$. By contrast, these values were low for negative $u_{l}$, in connection with the amplification of $w_{s}$ and $\unicode[STIX]{x1D706}_{y}$ by the strong spanwise motions of the positive $u_{l}$. The resultant skin friction induced by the amplified vortical motions within $u_{l}^{+}>2$ was responsible for 15 % of the total skin friction generated by the change-of-scale effect. Finally, we applied this analysis to a drag-reduced flow and found that the amplified vortical motions within the footprint of positive $u_{l}$ were markedly diminished, which ultimately contributed to the total drag reduction.

An accessory navicular bone (AN) is the most common accessory ossicle in the foot. The presence of an AN bone can trigger various foot problems, such as posterior tibial tendon pathology, flattening of the medial longitudinal arch, and medial foot pain. Despite the clinical influence of presence of an AN in foot disease, the research regarding its inheritance is still insufficient. A total of 135 pairs of monozygotic (MZ) twins, 25 pairs of dizygotic (DZ) twins, and 676 singletons from families were enrolled in order to estimate genetic influences on AN. After confirmation of zygosity and family relationship with a tandem repeat marker kit and questionnaires, the presence and type of the AN was classified through bilateral feet radiographic examination. The heritability of an AN was estimated using quantitative genetic analysis based on a variance decomposition model considering various types of family relationships: father–offspring pair, mother–offspring pair, and pooled DZ twin and sibling pairs. As a result, approximately 40.96% of the participants in this study had an AN in either foot, with type II being the most common type. The heritability for the presence of any type of an AN in any foot was estimated as 0.88 (95% CI [0.82, 0.94]) after adjusting for age and sex. Specifically, type II AN showed the highest heritability of 0.82 (95% CI [0.71–0.93]). The high heritability of an AN found in this large twin and family study suggests that an AN is determined by the substantial influence of genetic factor.

Direct numerical simulation data from turbulent pipe and channel flows at $\mathit{Re}_{\unicode[STIX]{x1D70F}}\approx 930$ are used to investigate their statistical difference by focusing on large-scale motions (LSMs). The contribution to the bulk production of turbulent kinetic energy shows marked differences in the overlap and core regions. These discrepancies arise from the dominant contributions of the LSMs ($\unicode[STIX]{x1D706}_{x}>3\unicode[STIX]{x1D6FF}$) to the Reynolds shear stress in the channel flow. The spectrum of the net Reynolds shear force reveals that the LSMs accelerate the mean flow in the overlap region. The net force spectrum is further decomposed into the spectra of velocity–vorticity correlations, $\langle v\unicode[STIX]{x1D714}_{z}\rangle$ and $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$, which are related to the advective vorticity transport and the change-of-scale effect, respectively. The dominance of large-scale accelerating motions (LSAMs) in the overlap region of the channel flow is due to the contribution of $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$ at longer wavelengths ($\unicode[STIX]{x1D706}_{x}>3\unicode[STIX]{x1D6FF}$), The LSAMs are related to the long low-speed regions, and these regions are longer and wider in the channel flow than in the pipe flow. Due to the pipe curvature, the spanwise size of the LSMs is restricted by neighbouring LSMs and the spanwise velocity fluctuations are reduced. The contribution of $\langle -w\unicode[STIX]{x1D714}_{y}\rangle$ to the acceleration is prominent in the channel flow, leading to the dominance of the LSAMs associated with the change-of-scale effect.

Direct numerical simulation data of turbulent channel flow ($Re_{{\it\tau}}=930$) are used to investigate the statistics of long motions of streamwise velocity fluctuations ($u$), and the interaction of these structures with the near-wall disturbances, which is facilitated by their associated large-scale circulations. In the log layer, the negative-$u$ structures are organized into longer streamwise extent (${>}3{\it\delta}$) in comparison to the positive-$u$ counterparts. Near the wall, the footprint of negative-$u$ structures is relatively narrow in comparison to the footprint of positive-$u$ structures. This difference is due to the opposite spanwise motions in the vicinity of the footprints, which are either congregative or dispersive depending on the circulation of the outer roll cells. Conditional sampling of the footprints shows that the spanwise velocity fluctuations ($w$) are significantly enhanced by the dispersive motions of high-speed structures. On the other hand, the near-wall congregative motions of negative-$u$ structures generate relatively weak $w$ but intense negative-$u$ regions due, in part, to the spanwise collective migration of near-wall streaks. The concentrated near-wall regions of negative-$u$ upwell during the merging of the outer long scales – an effect that is demonstrated using statistical analysis of the merging process. This leads to a reduction of the convection speed of downstream negative-$u$ structures and thus promotes the merging with upstream ones. These top-down and bottom-up interactions enhance the spatial coherence of long negative-$u$ structures in the log region.

In interpreting radiocarbon dating results, it is important that archaeologists distinguish uncertainties derived from random errors and those from systematic errors, because the two must be dealt with in different ways. One of the problems that archaeologists face in practice, however, is that when receiving dating results from laboratories, they are rarely able to critically assess whether differences between multiple 14C dates of materials are caused by random or systematic errors. In this study, blind tests were carried out to check four possible sources of errors in dating results: repeatability of results generated under identical field and laboratory conditions, differences in results generated from the same sample given to the same laboratory submitted at different times, interlaboratory differences of results generated from the same sample, and differences in the results generated between inner and outer rings of wood. Five charred wood samples, collected from the Namgye settlement and Hongreyonbong fortress, South Korea, were divided into 80 subsamples and submitted to five internationally recognized 14C laboratories on a blind basis twice within a 2-month interval. The results are generally in good statistical accordance and present acceptable errors at an archaeological scale. However, one laboratory showed a statistically significant variance in ages between batches for all samples and sites. Calculation of the Bayesian partial posterior predictive p value and chi-squared tests rejected the null hypothesis that the errors randomly occurred, although the source of the error is not specifically known. Our experiment suggests that it is necessary for users of 14C dating to establish an organized strategy for dating sites before submitting samples to laboratories in order to avoid possible systematic errors.

With regard to the survey data of Korean researchers using genetic resources from three genebanks administered by the Korea Research Institute of Bioscience and Biotechnology, we conducted conjoint and cluster analyses to estimate the relative importance of genetic resource (microbial, plant and animal) attributes among the researchers. Our results indicate that Korean researchers view price (cost of acquiring an accession), high new functionality (functional properties of germplasms for specific applications and uses) and completely uncovered genomic information (about mutation, genetic transformation, genomic function and pathways) as far more important in decision-making about R&D use of microbial, plant and animal genetic resources, respectively, than other attributes. Furthermore, this study shows that researchers conducting R&D in the microbial and plant genetic resource sectors especially prefer resources from specific domestic environments and Korean indigenous species, respectively. The study also sheds light on different patterns of researcher segments in terms of utilities of attributes and subgroups of researchers who have common needs in the three genetic resource sectors. We proposed some policy and strategic implications based on the results of this study.

A trend toward greater body size in dizygotic (DZ) than in monozygotic (MZ) twins has been suggested by some but not all studies, and this difference may also vary by age. We analyzed zygosity differences in mean values and variances of height and body mass index (BMI) among male and female twins from infancy to old age. Data were derived from an international database of 54 twin cohorts participating in the COllaborative project of Development of Anthropometrical measures in Twins (CODATwins), and included 842,951 height and BMI measurements from twins aged 1 to 102 years. The results showed that DZ twins were consistently taller than MZ twins, with differences of up to 2.0 cm in childhood and adolescence and up to 0.9 cm in adulthood. Similarly, a greater mean BMI of up to 0.3 kg/m2 in childhood and adolescence and up to 0.2 kg/m2 in adulthood was observed in DZ twins, although the pattern was less consistent. DZ twins presented up to 1.7% greater height and 1.9% greater BMI than MZ twins; these percentage differences were largest in middle and late childhood and decreased with age in both sexes. The variance of height was similar in MZ and DZ twins at most ages. In contrast, the variance of BMI was significantly higher in DZ than in MZ twins, particularly in childhood. In conclusion, DZ twins were generally taller and had greater BMI than MZ twins, but the differences decreased with age in both sexes.

For over 100 years, the genetics of human anthropometric traits has attracted scientific interest. In particular, height and body mass index (BMI, calculated as kg/m2) have been under intensive genetic research. However, it is still largely unknown whether and how heritability estimates vary between human populations. Opportunities to address this question have increased recently because of the establishment of many new twin cohorts and the increasing accumulation of data in established twin cohorts. We started a new research project to analyze systematically (1) the variation of heritability estimates of height, BMI and their trajectories over the life course between birth cohorts, ethnicities and countries, and (2) to study the effects of birth-related factors, education and smoking on these anthropometric traits and whether these effects vary between twin cohorts. We identified 67 twin projects, including both monozygotic (MZ) and dizygotic (DZ) twins, using various sources. We asked for individual level data on height and weight including repeated measurements, birth related traits, background variables, education and smoking. By the end of 2014, 48 projects participated. Together, we have 893,458 height and weight measures (52% females) from 434,723 twin individuals, including 201,192 complete twin pairs (40% monozygotic, 40% same-sex dizygotic and 20% opposite-sex dizygotic) representing 22 countries. This project demonstrates that large-scale international twin studies are feasible and can promote the use of existing data for novel research purposes.