The dendrite morphologies of the cast nickel-based superalloy CMSX-4® (CMSX-4® is registered trademarks of the Cannon-Muskegon Corporation) and the austenitic stainless steel HP microalloy have been obtained via an automated serial-sectioning process which allows three-dimensional (3D) microstructural characterization. The dendrite arm spacing, volume fraction of segregation, and fraction of porosity have been determined. This technique not only increases the depth, scope, and level of detailed microstructural characterization but also delivers microstructural data for modeling and simulation.

Lymphatic filariasis is a neglected tropical disease caused by roundworm parasites such as Brugia malayi that spread via a mosquito vector. In vitro culture of these parasites provides controlled conditions to understand parasite biology and provides a cheaper way to screen potential micro- and macrofilaricides. Published studies have used a wide array of approaches and metrics regarding in vitro cultures of B. malayi; as a result, drawing comparisons and identifying the reasons why inability to reproduce outcomes are difficult. This study sought to determine conditions that ensure reproducible outcomes and used evaluation metrics that are easily measured and can be automated to ensure objectivity. We found culturing B. malayi third-stage larvae (L3) in endothelial basal media supplemented with 20% fetal bovine serum and 75 µ m ascorbic acid in a temperature- and humidity-controlled incubator produced better survival and molting rates as well as longer and more motile parasites than previously reported. The benefit of ascorbic acid seemed to be unique to L3 parasites, as the addition of ascorbic acid to adult parasites had no significant impact on survival or motility. The methods reported in this study will help in designing experiments for both parasite behaviour studies and drug screening applications for disease eradication.

Epitaxial Ge films are useful as a substrate for high-efficiency solar cell applications. It is possible to grow epitaxial Ge films on low cost, cube textured Ni(001) sheets using CaF2(001) as a buffer layer. Transmission electron microscopy (TEM) analysis indicates that the CaF2(001) lattice has a 45o in-plane rotation relative to the Ni(001) lattice. The in-plane epitaxy relationships are CaF2[110]//Ni[100] and CaF2[ $\bar 1$ 10]//Ni[010]. Energy dispersive spectroscopy (EDS) shows a sharp interface between Ge/CaF2 as well as between CaF2/Ni. Electron backscatter diffraction (EBSD) shows that the Ge(001) film has a large grain size (∼50 μm) with small angle grain boundaries (< 8o). The epitaxial Ge thin film has the potential to be used as a substrate to grow high quality III-V and II-VI semiconductors for optoelectronic applications.

Loess deposits in the Vojvodina region, northern Serbia, are among the oldest and most complete loess-paleosol sequences in Europe to date. These thick sequences contain a detailed paleoclimatic record from the late Early Pleistocene. Based on the correlation of detailed magnetic susceptibility (MS) records from Vojvodina with the Chinese loess record and deep-sea isotope stratigraphy we here reconfirm and expand on a stratigraphic model of the Vojvodinian loess-paleosol chronostratigraphic sequence following the Chinese loess stratigraphic system.

Variations in MS, dust accumulation rates, and the intensity of pedogenesis demonstrate evidence for a Middle Pleistocene climatic and environmental transition. The onset of loess deposition in Vojvodina also indicates a direct link between dust generation in Europe and that in the interior of Eurasia since the Early Pleistocene. The youngest part of the Early Pleistocene and oldest part of the Middle Pleistocene is characterised by relatively uniform dust accumulation and soil formation rates as well as relatively high magnetic susceptibility values. In contrast, the last five interglacial-glacial cycles are characterised by sharp environmental differences between high dust accumulation rates during the glacials and low rates observed during soil development. The data presented in this study demonstrate the great potential of Vovjodina's loess archives for accurate reconstruction of continental Eurasian Pleistocene climatic and environmental evolution.

Often, silver nanoparticles (AgNps) are looked at in the realm of their plasmonic effects that are characterized by unique absorptional bands in the visible spectrum. Herein, the kinetics of a simple gravity mediated sedimentation process of AgNps, in aqueous suspensions. The surface energy mismatch between the AgNps and the receiver substrate allow for the formation of irregularly shaped AgNp microclusters with interconnected microchannels with dimensions and particle density controlled by the distance between the exposed substrate surface and the water/suspension interface. An investigation of the interplay between these properties and the films’ nanoparticle density is presented.

A study of the formation mechanisms of foamy coatings on the surface of glass-ceramic substrates produced by laser ablation is presented. Three laser systems emitting at 1064, 532 and 355 nm with pulse-widths in the nanosecond range were used. In the NIR range the formation of the coating is only possible when the temperature of the surface is higher than 300 ºC. In this case, the generation is related to an increase of the layer in liquid-phase produced in the interaction zone. However, when the sample is machined at 532 or 355 nm, it is not necessary to heat the whole surface to be processed. In this case, the local temperature and the pressure exerted over the interaction zone produce the generation of this coating, obtaining the layer at room temperature. Furthermore, the coating can be produced at higher speeds. In this way, it is possible to reduce the energetic cost improving the efficiency of the process.

Morphology, microstructure, composition and thermal properties of the layer are described.

A mechanical vibration system was made by sandwiching an array of parylene-C microsprings between two flat plates of Si. This system was driven mechanically in forced oscillation using a piezo transducer attached to the bottom Si plate. An atomic force microscope was used to record the displacement of the top plate in both the contact and non-contact modes. At the resonance, the system was observed to give large vertical displacement amplitude of up to 100 nm with a Q-factor of up to 900.

Fully nonlinear electrostatic waves in a plasma containing electrons, positrons, and ions are investigated by solving the governing equations exactly. It is found that both smooth and spiky quasistationary waves exist, and large-amplitude waves necessarily have large-phase velocities, but small-amplitude waves can be both fast and slow.

Knowledge of the control of the musculoskeletal system in patients with knee osteoarthritis (OA) during gait is helpful for the development of intervention programs in the management of these patients. The current study aimed to investigate the leg and joint stiffness, aswell as the associated joint kinematics and kinetics, in patients with bilateral medial knee OA during gait. Joint angles, moments and stiffness, as well as leg stiffness from fifteen patients with bilateral knee OA and fifteen normal controls during level walking, were obtained and their values at the beginning and end of single leg stance were compared using a t-test.

Patients with knee OA were found to modulate their leg and joint stiffness through acquired specific biomechanical strategies in order to maintain normal temporal-spatial patterns of gait. During weight acceptance, they increased their leg stiffness with increased knee stiffness but unalterd hip and ankle stiffness. During weight release, they modulated their hip and ankle kinetics with increased knee and ankle stiffness to improve the control stability of the limb with unaltered leg stiffness. It is suggested that muscle strengthening exercise intervention and/or rehabilitation for patients with knee OA should focus on activities that develop and/or maintain functions not only of the knee, but also of the overall lower extremity.