Although glacial landscapes have previously been used for the reconstruction of late Quaternary glaciations in the Central Andes, only few data exist for the Eastern Cordillera in Bolivia. Here, we present results from detailed morphostratigraphic mapping and new data of surface exposure dating (SED), optically stimulated luminescence (OSL), and radiocarbon dating (14C) from the Huara Loma Valley, Cordillera de Cochabamba (Bolivia). Discrepancies between individual dating methods could be addressed within the context of a solid geomorphic framework. We identified two major glaciations. The older is not well constrained by the available data, whereas the younger glaciation is subdivided into at least four major glacial stages. Regarding the latter, a first advance dated to ~ 29–25 ka occurred roughly contemporaneous with the onset of the global last glacial maximum (LGM) and was followed by a less extensive (re-)advance around 20–18 ka. The local last glacial maximum (LLGM) in the Huara Loma Valley took place during the humid lateglacial ~17–16 ka, followed by several smaller readvances until ~10–11 ka, and complete deglaciation at the end of the Early Holocene.