Light-driven micromanipulators have been developed by two-photon microstereolithography. The manipulators are driven and controlled by optical trapping. The torque of micromanipulator was successfully controlled on the order of femto-newton by adjusting the focal position of the trapped laser beam. Nanotweezers and a nanoneedle with probe tip of diameter 250 nm were fabricated and driven in a liquid. Such remote-controlled manipulation tools provide a unique and effective handling method of biological samples such as living cell, protein and DNA.