At present, industrial scenes with sparse features and weak textures are widely encountered, and the three-dimensional reconstruction of such scenes is a recognized problem. Pressure pipelines have a wide range of applications in fields such as petroleum engineering, chemical engineering, and hydropower station engineering. However, there is no mature solution for the three-dimensional reconstruction of pressure pipes. The main reason is that the typical scenes in which pressure pipes are found also have relatively few features and textures. Traditional three-dimensional reconstruction algorithms based on feature extraction are largely ineffective for such scenes that are lacking in features. In view of the above problems, this paper proposes an improved interframe registration algorithm based on point cloud fitting with cylinder axis vector constraints. By incorporating geometric feature parameters of a cylindrical pressure pipeline, specifically the axis vector of the cylinder, to constrain the traditional iterative closest point algorithm, the accuracy of point cloud registration can be improved in scenarios lacking features and textures, and some environmental uncertainties can be overcome. Finally, using actual laser point cloud data collected from pressure pipelines, the proposed fitting-based point cloud registration algorithm with cylinder axis vector constraints is tested. The experimental results show that under the same conditions, compared with other open-source point cloud registration algorithms, the proposed method can achieve higher registration accuracy. Moreover, integrating this algorithm into an open-source three-dimensional reconstruction algorithm framework can lead to better reconstruction results.

In this paper, the ordering properties of convex and increasing convex orders of the dependent random variables are studied. Some closure properties of the convex and increasing convex orders under independent random variables are extended to the dependent random variables under the Archimedean copula. Two applications are provided to illustrate our results.

Dietary antioxidant indices (DAI) may be potentially associated with relative telomere length (RTL) of leucocytes. This study aimed to investigate the relationship between DAI and RTL. A cross-sectional study involving 1656 participants was conducted. A generalised linear regression model and a restricted cubic spline model were used to assess the correlation of DAI and its components with RTL. Generalised linear regression analysis revealed that DAI (β = 0·005, P = 0·002) and the intake of its constituents vitamin C (β = 0·043, P = 0·027), vitamin E (β = 0·088, P < 0·001), Se (β = 0·075, P = 0·003), and Zn (β = 0·075, P = 0·023) were significantly and positively correlated with RTL. Sex-stratified analysis showed that DAI (β = 0·006, P = 0·005) and its constituents vitamin E (β = 0·083, P = 0·012), Se (β = 0·093, P = 0·006), and Zn (β = 0·092, P = 0·034) were significantly and positively correlated with RTL among females. Meanwhile, among males, only vitamin E intake (β = 0·089, P = 0·013) was significantly and positively associated with RTL. Restricted cubic spline analysis revealed linear positive associations between DAI and its constituents’ (vitamin E, Se and Zn) intake and RTL in the total population. Sex-stratified analysis revealed a linear positive correlation between DAI and its constituents’ (vitamin E, Se and Zn) intake and RTL in females. Our study found a significant positive correlation between DAI and RTL, with sex differences.

When motile algal cells are exposed to gyrotactic torques, their swimming directions are guided to form radial accumulation, well known as hydrodynamic focusing. The origin of hydrodynamic focusing from the effects of active swimming, ambient flow and particle anisotropy is elucidated in the present study on the pre-asymptotic dispersion of active particles through a vertical pipe. With an extension of the Galerkin method to pipe flows, time-dependent solutions directly from the Smoluchowski equation in the position and orientation space are derived by series expansions of spherical harmonics and Bessel functions. Ballistic and diffusive scaling laws are examined with the predominance of self-propelled swimming, and computation is validated against an explicit benchmark solution and Lagrangian particle simulation. In the limit of extreme shear, the competitive roles of shear dispersion and Brownian rotation are reflected concretely in the pre-asymptotic phase of hydrodynamic focusing. For flows with various shear strengths, a concentration peak in near-wall regions with a smooth transition to hydrodynamic focusing is illustrated with richer phenomena in upwelling and downwelling flows. A newly observed regime through a vertical pipe, named transient effective trapping, is revealed as a transitional mode towards hydrodynamic focusing. The pre-asymptotic approach to hydrodynamic focusing is elaborated intensively through extensive solutions of concentration moments and macroscopic transport coefficients characterised by swimming and flow Péclet numbers. The unique findings for the origin of hydrodynamic focusing could provide insight into related micro-algae reactor technology and contribute to flow control and biomass transfer in confined environments.

Coastal eutrophication and hypoxia remain a persistent environmental crisis despite the great efforts to reduce nutrient loading and mitigate associated environmental damages. Symptoms of this crisis have appeared to spread rapidly, reaching developing countries in Asia with emergences in Southern America and Africa. The pace of changes and the underlying drivers remain not so clear. To address the gap, we review the up-to-date status and mechanisms of eutrophication and hypoxia in global coastal oceans, upon which we examine the trajectories of changes over the 40 years or longer in six model coastal systems with varying socio-economic development statuses and different levels and histories of eutrophication. Although these coastal systems share common features of eutrophication, site-specific characteristics are also substantial, depending on the regional environmental setting and level of social-economic development along with policy implementation and management. Nevertheless, ecosystem recovery generally needs greater reduction in pressures compared to that initiated degradation and becomes less feasible to achieve past norms with a longer time anthropogenic pressures on the ecosystems. While the qualitative causality between drivers and consequences is well established, quantitative attribution of these drivers to eutrophication and hypoxia remains difficult especially when we consider the social economic drivers because the changes in coastal ecosystems are subject to multiple influences and the cause–effect relationship is often non-linear. Such relationships are further complicated by climate changes that have been accelerating over the past few decades. The knowledge gaps that limit our quantitative and mechanistic understanding of the human-coastal ocean nexus are identified, which is essential for science-based policy making. Recognizing lessons from past management practices, we advocate for a better, more efficient indexing system of coastal eutrophication and an advanced regional earth system modeling framework with optimal modules of human dimensions to facilitate the development and evaluation of effective policy and restoration actions.

Progressive capillary waves on the interface between two homogeneous fluids confined in a channel with rigid walls parallel to the undisturbed interface are investigated. This problem is formulated as a system of integrodifferential equations that can be solved numerically via a boundary integral equation method coupled with series expansions of the unknown functions. With this highly accurate scheme and numerical continuation, we explore the global bifurcation of periodic travelling waves. It is found that there are two types of limiting profile, self-intersecting and boundary-touching, which appear either along a primary branch bifurcating from infinitesimal periodic waves or on an isolated branch existing above a certain finite amplitude. For particular sets of parameters, these two types of bifurcation curves can intersect, which can be viewed as a secondary bifurcation phenomenon occurring on the primary branch. Based on asymptotic and numerical analyses of the almost limiting waves, it is found that the boundary-touching solutions feature a circular geometry, i.e. the interface is pieced together by circular arcs of the same radius. A theoretical investigation yields the necessary conditions for the existence of these extreme waves, whereby we can predict the limiting configurations for most parameter sets. The comparisons between theoretical predictions and numerical results show good agreement.

During the current global COVID-19 crisis Taiwan has portrayed itself as both an example for other countries to follow and as a country willing to assist others in their own efforts with the virus. Taiwan has also renewed efforts to participate in the World Health Organization (WHO), an organisation from which it is currently excluded. Although some countries have supported Taiwan's efforts to participate in the WHO or have praised its COVID-19 response, others have been silent or even critical, sometimes citing commitments to a “one China policy.” In this paper, we use newly collected data to explore cross-national variation in support for Taiwan during the current pandemic. We find that a country's level of economic development and security ties with the US are strongly correlated with support for Taiwan while a country's economic ties to China is a less consistent predictor.

In the past 10–15 years, the government of China has made various efforts in tackling excessive antibiotics use. Yet, little is known about their effects at rural primary care settings. This study aimed to determine the impact of government policies and the COVID-19 pandemic on antibiotic prescribing practices at such settings utilizing data from separate studies carried out pre- and during the pandemic, in 2016 and 2021 in Anhui province, China, using identical sampling and survey approaches. Data on antibiotics prescribed, diagnosis, socio-demographic, etc., were obtained through non-participative observation and a structured exit survey. Data analysis comprised mainly descriptive comparisons of 1153 and 762 patients with respiratory infections recruited in 2016 and 2021, respectively. The overall antibiotics prescription rate decreased from 89.6% in 2016 to 69.1% in 2021, and the proportion of prescriptions for two or more classes of antibiotics was estimated as 35.9% in 2016 and 11.0% in 2021. There was a statistically significant decrease in the number of days from symptom onset to clinic visits between the year groups. In conclusion, measures to constrain excessive prescription of antibiotics have led to some improvements at the rural primary care level, and the COVID-19 pandemic has had varying effects on antibiotic use.

Drawing on social cognitive theory, this paper examines whether self-reflection mediates the association between workplace ostracism and team members' creativity, and whether this mediating effect is moderated by high-involvement work practices (HIWPs). We construct and test a cross-level model using multilevel path analysis to analyse data collected from 81 teams (a total of 393 members) in China. The results show that workplace ostracism negatively influences team members' reflection but positively influences rumination, which in turn affects individual creativity. Furthermore, HIWPs negatively moderate the effects of workplace ostracism on self-reflection, and moderate the linkages among workplace ostracism, reflection/rumination and team members' creativity. Finally, theoretical and practical implications of these findings are discussed.

Interfacial waves between two superimposed dielectric fluid layers under a horizontal electric field are investigated from asymptotic and numerical aspects. The fluid is taken to be inviscid, incompressible and non-conducting in each layer. The competing forces resulting from gravity, surface tension and electric field are all considered. A systematic procedure is proposed to derive model equations of multiple scales in various possible limits from the electrified Euler equations in the framework of the Zakharov–Craig–Sulem formulation. Based on thorough analyses of the Dirichlet–Neumann operators in the long-wave approximation, classic weakly nonlinear models – including the Boussinesq-type system, the Korteweg–de Vries (KdV) equation and its variants, and the Benjamin-type equation – are obtained under different scaling assumptions. In addition, strongly nonlinear models (without the smallness assumption on the wave amplitude) in the Benjamin and Barannyk–Papageorgiou–Petropoulos regimes are derived. In these models, the electric effects are shown to produce dispersive regularisations of long and short waves. A modified boundary integral equation method is developed to compute solitary waves in the original electrified Euler equations. Through comparisons with solitary-wave solutions in the Euler equations, it is found that in various asymptotic regimes, weakly nonlinear models are in overall good agreement when wave amplitudes are small. In contrast, the range of validity of the strongly nonlinear model is much broader. It is shown that the horizontal electric field plays a significant role in the physical system: it expands the range of parameters for the existence of progressive waves, changes the qualitative characteristics of solitary waves and leads to a new type of solitary wave, namely the KdV–wavepacket mixed type.

Two-dimensional periodic interfacial gravity waves travelling between two homogeneous fluids of finite depth are considered. A boundary-integral-equation method coupled with Fourier expansions of the unknown functions is used to obtain highly accurate solutions. Our numerical results show excellent agreement with those already obtained by Maklakov & Sharipov using a different scheme (J. Fluid Mech., vol. 856, 2018, pp. 673–708). We explore the global bifurcation mechanism of periodic interfacial waves and find three types of limiting wave profiles. The new families of solutions appear either as isolated branches or as secondary branches bifurcating from the primary branch of solutions.

The staining procedure is critical for investigating intra- and extra-cellular ultrastructure of microorganisms by transmission electron microscopy (TEM). Here, we propose a new ultra-low lead staining (ULLS) technique for preparing the ultrathin sections for TEM analysis. Sections of Enterobacter sp. (bacteria), Aspergillus niger (filamentous fungi), Rhodotorula mucilaginosa (fungi), and Chlamydomonas reinhardtii (microalgae) were tested. Compared with the sections prepared by the typical double-staining technique, ULLS-based sections showed evident advantages: (i) the staining process only required the addition of Pb(NO3)2; (ii) the Pb level during incubation was set as low as 1 mg/L, which had negligible toxicity to most microbial cells; (iii) the Pb cations were added during microbial culture, which avoided complicated sample preparation as in typical double staining. Taking C. reinhardtii as an example, the ULLS technique allowed fine investigation of microbial ultrastructure, e.g., starch granule, mitochondrion, Golgi apparatus, vacuole, and vesicle. Meanwhile, the physiological processes of the cells such as cell lysis and exocytosis were successfully captured, with relatively high contrast. This study hence shows a bright future on preparation of the high-quality ultrathin sections of microbial cells by the ULLS technique.

The limiting configuration of interfacial solitary waves between two homogeneous fluids consisting of a sharp $120^{\circ }$ angle with an enclosed bubble of stagnant heavier fluid on top is investigated numerically. We use a boundary integral equation method to compute the almost limiting profiles which are nearly self-intersecting and thus extend the work of Pullin & Grimshaw (Phys. Fluids, vol. 31, 1988, pp. 3550–3559) by obtaining the overhanging solutions for very small density ratios. To further study the local configuration of the limiting profile, we propose a reduced model that replaces the $120^{\circ }$ angle with two straight solid walls intersecting at the bottom of the bubble. Using a series truncation method, a one-parameter family of solutions depending on the angle between the two solid walls (denoted by $\gamma$) is found. When $\gamma = {2{\rm \pi} }/{3}$, it is shown that the simplified model agrees well with the near-limiting wave profile if the density ratio is small, and thus provides a good local approximation to the assumed limiting configuration. Interesting solutions for other values of $\gamma$ are also explored.

This paper is concerned with the interaction of vertically sheared currents with two-dimensional flexural–gravity waves in finite depth. A third-order Stokes expansion is carried out and fully nonlinear computations are performed for symmetric, steadily travelling waves on a linear shear current. For upstream periodic waves, two global bifurcation mechanisms are discovered. Both branches bifurcate from infinitesimal periodic waves, with one stopping at another infinitesimal wave of different phase speed, and the other terminating at a stationary configuration. Generalised solitary waves are found for downstream waves. More surprisingly, the central pulse of the generalised solitary wave can become wide and flat as the computational domain is enlarged. This provides strong evidence for the existence of wave fronts in single-layer free-surface waves. Particle trajectories and streamline structures are studied numerically for the fully nonlinear equations. Two patterns, closed orbits and pure horizontal transport, are observed for both periodic and solitary waves in moving frames. The most striking phenomenon is the existence of net vertical transport of particles beneath some solitary waves due to wave–current interactions. The streamline patterns alternate between net vertical transport and a closed orbit, resulting in the formation of a series of nested cat's-eye structures.

Probiotics and plant extracts are considered to prevent the development of non-alcoholic fatty liver disease (NAFLD). The present study explores the effects of using both probiotics and plant extracts on NAFLD. The present study evaluated the effects of plant extracts on lipid droplet accumulation and the growth of probiotics in vitro. A C57BL/6 mouse model was used to examine the effects of probiotics and plant extracts on NAFLD. Body weight and food intake were measured. The levels of serum lipids, oxidative stress and the liver injury index were determined using commercial kits. Haematoxylin and eosin staining, GC and real-time PCR were also used for analysis. The results revealed that administration of Lactobacillus casei YRL577 and L. paracasei X11 with resveratrol (RES) or tea polyphenols (TP) significantly reduced the levels of total cholesterol, TAG and LDL-cholesterol and increased the level of the HDL-cholesterol. The groups of L. casei YRL577 with RES and TP also regulated the liver structure, oxidative stress and injury. Furthermore, L. casei YRL577 with TP exhibited a more positive effect towards improving the NAFLD and increased the concentrations of the butyric acid than other three combined groups. L. casei YRL577 with TP up-regulated the mRNA levels of the farnesoid X receptor and fibroblast growth factor 15 and decreased the mRNA levels of the apical Na-dependent bile acid transporter. These findings showed that L. casei YRL577 + TP-modified genes in the intestinal bile acid pathway improved markers of NAFLD.

Maltreatment adversely impacts the development of children across a host of domains. One way in which maltreatment may exert its deleterious effects is by becoming embedded in the activity of neurophysiological systems that regulate metabolic function. This paper reviews the literature regarding the association between childhood maltreatment and the activity of three systems: the parasympathetic nervous system, the sympathetic nervous system, and the hypothalamic–pituitary–adrenal axis. A particular emphasis is placed on the extent to which the literature supports a common account of activity across these systems under conditions of homeostasis and stress. The paper concludes with an outline of directions for future research and the implications of the literature for policy and practice.

The purpose of this study was to construct a glycyrrhetinic acid (GA)-mediated, breakable, intracellular, nanoscale drug-delivery carrier via amide and esterification reactions. The structures were identified by Fourier-transformed infrared (FTIR) and 1H-nuclear magnetic resonance (1H-NMR) spectrophotometry. The compatibility and safety of the carrier were evaluated using hemolysis and cytotoxicity tests. The GA-copolymer micelle was prepared using the solvent evaporation method. FTIR and 1H-NMR detection demonstrated the successful construction of the polymer. No hemolysis occurred in any concentration of polymer within 3 h, and the hemolysis rate was less than 5%. 3-(4,5-dimethyl-thiazol-2-yl)-2,5-diphenyl-tetrazolium bromide (MTT) experimental results showed that the novel polymer reduced the cell survival rate and had significant cytotoxic effects. The blank nanoparticles were liquid with light blue opalescence. Transmission electron microscopy revealed that the empty micelles were uniform spheres, with an average size of 62 nm and a zeta potential of −13 mV. The novel GA-mediated polymeric carrier material developed here has the potential to effectively kill human SMMC-7721 cancer cells within 3 days when the dose is above 500 ug/mL.