The crystal structure of Cr2[Ni(CN)4]3·10H2O has been determined on X-ray diffraction powder data by means of the Rietveld method. The starting model was based on the isomorphic, disordered structure of Mn3[Co(CN)6]2·12H2O. At room temperature the crystal is cubic, F4¯3m, a=10.097(6) Å, V=1029.4(5) Å3. The structure is disordered and contains 1.33 formula weights per unit cell. The Ni and Cr ions are coordinated by N and C atoms, respectively, forming octahedra linked by CN groups. The water molecules replace partly the chromium, carbon, and nitrogen positions in the crystal. The final R values are: Rwp=0.032 (Rexp=0.023), RB=0.088, and DW-Stat.=1.31 (DWexp=1.8).