Field research was conducted to evaluate plant growth-regulator efficacy for tall fescue growth and seedhead suppression applied using application placement equipment. Specially designed equipment outfitted with fluid application systems applies low-volume plant growth regulator directly on plant foliage, reducing opportunity for drift and visible application. Wet-blade mowers are equipped to apply plant growth regulators and mow in a single pass, whereas rotary-wick applicators simply wipe chemicals directly on uncut vegetation. Therefore, a wet-blade, rotary-wick, and broadcast sprayer system were chosen to apply imazapic at three rates (9, 35, and 53 g ai/ha), and a mefluidide + chlorsulfuron tank mix at 7 + 140 g ai/ha to tall fescue roadsides for vegetative growth and seedhead suppression. Experiments were conducted during the spring and summer of 2004 in central and western North Carolina. Tall fescue was slightly injured and discolored by all treatments but fully recovered by 2 mo after treatment. Imazapic suppressed new vegetative growth 3 mo after treatment compared with the nonmowed–nontreated control (16.1 cm of growth) and the mowed–nontreated control (21.1 cm) when applied with the rotary-wick applicator (8.5 cm) and broadcast sprayer (6.2 cm). However, differences in vegetative height primarily occurred when application placement equipment treatments were compared with nontreated vegetation as opposed to mowed–nontreated plants. Although mowed–nontreated and wet-blade–treated plots had more new vegetative growth, nonmowed–nontreated plots still consistently had the greatest vegetative height. Seedhead suppression ranged from 87 to 100% when compared with the nonmowed–nontreated control, with wet-blade treatments consistently providing the least-effective seedhead suppression. Overall, application placement equipment did not improve plant growth-regulator efficacy when compared with the foliar broadcast spray.