This terrestrial and underwater archaeological research project around a Mediterranean islet identifies that it was a commercial centre during the fifth century AD. The results shed light on Late Roman island occupation dynamics.

This study aimed to assess the impact of the introduction of pneumococcal conjugate vaccine 13 (PCV13) on the molecular epidemiology of invasive pneumococcal disease (IPD) in children from Andalusia. A population-based prospective surveillance study was conducted on IPD in children aged <14 years from Andalusia (2018–2020). Pneumococcal invasive isolates collected between 2006 and 2009 in the two largest tertiary hospitals in Andalusia were used as pre-PCV13 controls for comparison of serotype/genotype distribution. Overall IPD incidence rate was 3.55 cases per 100 000 in 2018; increased non-significantly to 4.20 cases per 100 000 in 2019 and declined in 2020 to 1.69 cases per 100 000 (incidence rate ratio 2020 vs. 2019: 0.40, 95% confidence interval (CI) 0.20–0.89, P = 0.01). Proportion of IPD cases due to PCV13 serotypes in 2018–2020 was 28% (P = 0.0001 for comparison with 2006–2009). Serotypes 24F (15%) and 11A (8.3%) were the most frequently identified non-PCV13 serotypes (NVT) in 2018–2020. Penicillin- and/or ampicillin-resistant clones mostly belonged to clonal complex 156 (serotype 14-ST156 and ST2944 and serotype 11A-ST6521). The proportion of IPD cases caused by PCV13 serotypes declined significantly after the initiation of the PCV13 vaccination programme in 2016. Certain NVT, such as serotypes 24F and 11A, warrant future monitoring in IPD owing to invasive potential and/or antibiotic resistance rates.

Our Palaeolithic ancestors did not make good representations of themselves on the rocky surfaces of caves and barring certain exceptions – such as the case of La Marche (found on small slabs of stone or plaquettes) or the Cueva de Ambrosio – the few known examples can only be referred to as anthropomorphs. As such, only hand stencils give us a real picture of the people who came before us. Hand stencils and imprints provide us with a large amount of information that allows us to approach not only their physical appearance but also to infer less tangible details, such as the preferential use of one hand over the other (i.e., handedness). Both new and/or mature technologies as well as digital processing of images, computers with the ability to process very high resolution images, and a more extensive knowledge of the Palaeolithic figures all help us to analyse thoroughly the hands in El Castillo cave. The interdisciplinary study presented here contributes many novel developments based on real data, representing a major step forward in knowledge about our predecessors.

This Research Reflection addresses the possibilities for Welfare Quality® to evolve from an assessment method based on data gathered on punctual visits to the farm to an assessment method based on sensor data. This approach could provide continuous and objective data, while being less costly and time consuming. Precision Livestock Farming (PLF) technologies enabling the monitorisation of Welfare Quality® measures are reviewed and discussed. For those measures that cannot be assessed by current technologies, some options to be developed are proposed. Picturing future dairy farms, the need for multipurpose and non-invasive PLF technologies is stated, in order to avoid an excessive artificialisation of the production system. Social concerns regarding digitalisation are also discussed.

Despite a proliferation of articles focused on consumer willingness-to-pay for locally produced foods, few studies have systemically considered the role of food identity in the price premium of local foods. This article uses primary and secondary data to fill that gap. Using data from 9,329 U.S. households, we identify what foods each state considers a part of their collective food identity. We then compare each state's collective food identity to the actual production within the state. Finally, we utilize a discrete choice experiment (N = 484) focused on a state with one such collective food identity to test whether a consumer's preference for local foods is a function of the collective food identity within the state. Results from the open-ended survey suggest that each state connects with their food production in unique ways and that not all state identities are consistent with actual agricultural production. Results from the discrete choice experiment suggest that consumers are more willing to pay a premium for the local food that is a part of their local food identity than for a similar product that is not a part of their local food identity. Our findings imply that future research on consumer preferences for local food systems should consider the relationship between food culture and geography.

In the interest of transparency, MRS is a co-publisher of this title. However, this review was requested and reviewed by an independent Book Review Board.

As a consequence of axenic growth and the elimination of accompanying bacterial flora, Entamoeba histolytica virulence decreases rapidly, and pathogenicity is lost. This paper evaluated the impact of vitamin supplementation on the pathogenicity of E. histolytica. Growth of E. histolytica trophozoites, cultured axenically in PEHPS (a Spanish acronym for the main ingredients – casein peptone, liver, pancreas extract and bovine serum) medium, with or without vitamins, exhibited a similar growth rate. However, the vitamin-enriched PEHPS preparations expressed 2.65 times more haemolytic activity (at 60 min: 98 vs 48%, P < 0.05), 2.5 times more phospholipase A2 activity at 150 min of incubation and generated more hepatic abscesses (88 vs 60%, P = 0.05) than the preparations without vitamins. The haemolytic and phospholipase A2 activity for the PEHPS − V preparations were restored following vitamin supplementation with A and D. These data highlight, for the first time, that vitamins and specifically vitamin A and D were essential for the recovery of amoebic virulence, lost through axenic growth.

Parkinson's disease and Alzheimer's disease are progressive nervous system disorders that affect physical and cognitive capacities of individuals, including memory loss, motion impairment, or problem-solving dysfunctions. Leisure activities are associated with reducing the risk of dementia and are preventive policies for delaying the cognitive impairment in later stages of those neurodegenerative diseases. Electronic games related to cognitive abilities are an easy and inexpensive alternative for stimulating brain activity in this kind of patients. The previous research demonstrated the acceptance of these activities in the environment of Connected TV when playing at home and in daily care centers. Interaction in Connected TV applications has its own particularities that influence the design of the interface, including the viewing distance, the type of interaction through a remote control or other techniques, the size of the screen, or the collectiveness of consumption. Iterative testing with patients of these groups revealed how the physical characteristics and cognitive impairment of these concrete end-users affect the human–computer interaction, offering guidelines and recommendations in good practices for the Smart TV interface design. On the other hand, data analytics extracted from the interaction and evolution of the game offer important information enabling the creation of estimation prediction models about the cognitive state of the patient.

Universal access on equal terms to audiovisual content is a key point for the full inclusion of people with disabilities in activities of daily life. As a real challenge for the current Information Society, it has been detected but not achieved in an efficient way, due to the fact that current access solutions are mainly based in the traditional television standard and other not automated high-cost solutions. The arrival of new technologies within the hybrid television environment together with the application of different artificial intelligence techniques over the content will assure the deployment of innovative solutions for enhancing the user experience for all. In this paper, a set of different tools for image enhancement based on the combination between deep learning and computer vision algorithms will be presented. These tools will provide automatic descriptive information of the media content based on face detection for magnification and character identification. The fusion of this information will be finally used to provide a customizable description of the visual information with the aim of improving the accessibility level of the content, allowing an efficient and reduced cost solution for all.

This article explores two fundamental dimensions in sociolinguistics: the dynamics of linguistic variation and change in international languages and the exploitation of data proceeding from significant countries. These issues will be addressed through examination of a particular syntactic feature and a possible change in progress: the occurrence of null direct objects in Spanish. It is shown that for Spanish, a widely used international language, social factors have not been decisive in explaining the distribution of the phenomenon under investigation. This study shows that while direct object omission is not conditioned by typical social variables such as sex, age, and gender, it is unevenly spread throughout the Spanish-speaking world: Mexico and the continental Caribbean use it more than other countries, such as Spain or Chile. Besides the relevance of geography, some semantic, discourse, and contextual factors are shown as determinant for the direct object omission. Finally, this paper reflects on methodology, specifically the use of a macroregional sociolinguistic method for data analysis as well as the advantages and shortcomings of a specific data collection technique that capitalizes on technological tools with global reach: the internet survey in an international scenario.

School performance is a critical aspect of adolescents’ lives. Several factors have an impact on school performance. The aim of this study is to analyze the relevant personal and contextual variables associated with top performance and low achievement in a sample of Portuguese and Spanish adolescent students. The sample included 1,564 adolescents, mean age 14 years old, and was collected from the HBSC (Health Behavior in School-aged Children) survey. The questions in this study covered sociodemographic, health and wellbeing, health-related behaviors, family, school and peers. Results show that students with low performance more frequently have worse social-contextual and personal/health-related indicators, while the opposite is the case for top performers. Student-teacher relationships appeared as the most influential variable on school performance paths, χ2(2) = 328.11, p < .001; but other variables within families, e.g. mother studies, χ2(2) = 50.54, p < .001, and schools, e.g. liking the school, χ2(1) = 16.27, p < .001 and χ2(1) = 22.54, p < .01 (in the low and high student-teacher relationship branches of the decision tree, respectively), as well as some health and wellbeing variables, e.g. health related-quality of life, χ2(2) = 53.58, p < .001, and χ2(2) = 63.86, < .001 (in the low and high student-teacher relationship branches, respectively), appeared significant in the paths.

Highlighting the dispersal ecology of parasites is important for understanding epidemiological, demographic and coevolutionary aspects of host–parasite interactions. Yet, critical aspects of the dispersal stage of parasites, such as longevity and the factors influencing it, are poorly known. Here we study the lifespan of the dispersal stage of an ectoparasitic dipteran, Carnus hemapterus, and the impact of gender, body size and food provisioning on longevity. We found that freshly emerged imagoes survive at most less than 4 days. Longevity increased with body size and, since this parasite exhibits sexual size dimorphism, the bigger females lived longer than males. However, controlling for body size suggests that males lived relatively longer than females. Furthermore, a humid environment and food provisioning (flowers) significantly increased individual life spans. We discuss the relative importance of spatial and temporal dispersal in relation to the infectious potential of this parasite.

Differentiation of niche by means of resource partitioning facilitates coexistence of species with similar requirements. Here we analyse the association between different habitats (i.e. nest types) and two Diptera species of the poorly known Family Carnidae that coexist during their larval and pupal stage in the nests of troglodytic bird species. We also describe for the first time the puparium of Hemeromyia anthracina and Hemeromyia longirostris and offer morphometric data of the puparia of these two species and of Carnus hemapterus. Both the smaller size and the occurrence of well-developed spiracles allow easy discrimination of the puparium of C. hemapterus. The puparia of both Hemeromyia species is very similar and only differ in the distance between the small spiracles. Hemeromyia anthracina and C. hemapterus coexisted in nest boxes but the former species did not occur in natural sandy cavities where, in turn, C. hemapterus was highly prevalent. Carnus hemapterus prevalence did not differ between nest boxes and natural cavities but its abundance was higher in the first type of nest. This study shows clear associations of the two dipteran species with specific types of nests. Yet, some conditions are seemingly acceptable for both species.

The aim of this study was to analyse the contribution of social support from family, friend and school (teacher and classmate) contexts in substance use (tobacco and alcohol use) and well-being (life satisfaction and health-related quality of life). Participants were 5,784 Portuguese and 22,610 Spanish adolescents aged 11 to 16 years, from the 2014 edition of the Health Behavior in School-aged Children (HBSC) study in Portugal and Spain. Results showed that for a higher life satisfaction, family (p < .001, partial η2 = .032), teacher (p < .001, partial η2 = .018) and classmate (p < .001, partial η2 = .031) support were important in Portugal, and family (p < .001, partial η2 = .056) and friend (p < .001, partial η2 = .015) support in Spain. Similarly, for a better health-related quality of life, all the social support variables were relevant in Portugal (family: p < .001, partial η2 = .063; teacher: p < .001, partial η2 = .032; classmate: p < .001, partial η2 = .054; friend: p < .001, partial η2 = .034) and in Spain (family: p < .001, partial η2 = .054; teacher: p < .001, partial η2 = .014; classmate: p < .001, partial η2 = .018; friend: p < .001, partial η2 = .040). In contrast, only family support (p < .001, partial η2 = .014) was relevant in Portugal for tobacco use. Therefore, social support was more relevant for adolescent well-being than for adolescent substance use, and the most relevant source of support was family support, in both Spain and Portugal.