NASA’s all-sky survey mission, the Transiting Exoplanet Survey Satellite (TESS), is specifically engineered to detect exoplanets that transit bright stars. Thus far, TESS has successfully identified approximately 400 transiting exoplanets, in addition to roughly 6 000 candidate exoplanets pending confirmation. In this study, we present the results of our ongoing project, the Validation of Transiting Exoplanets using Statistical Tools (VaTEST). Our dedicated effort is focused on the confirmation and characterisation of new exoplanets through the application of statistical validation tools. Through a combination of ground-based telescope data, high-resolution imaging, and the utilisation of the statistical validation tool known as TRICERATOPS, we have successfully discovered eight potential super-Earths. These planets bear the designations: TOI-238b (1.61$^{+0.09} _{-0.10}$ R$_\oplus$), TOI-771b (1.42$^{+0.11} _{-0.09}$ R$_\oplus$), TOI-871b (1.66$^{+0.11} _{-0.11}$ R$_\oplus$), TOI-1467b (1.83$^{+0.16} _{-0.15}$ R$_\oplus$), TOI-1739b (1.69$^{+0.10} _{-0.08}$ R$_\oplus$), TOI-2068b (1.82$^{+0.16} _{-0.15}$ R$_\oplus$), TOI-4559b (1.42$^{+0.13} _{-0.11}$ R$_\oplus$), and TOI-5799b (1.62$^{+0.19} _{-0.13}$ R$_\oplus$). Among all these planets, six of them fall within the region known as ‘keystone planets’, which makes them particularly interesting for study. Based on the location of TOI-771b and TOI-4559b below the radius valley we characterised them as likely super-Earths, though radial velocity mass measurements for these planets will provide more details about their characterisation. It is noteworthy that planets within the size range investigated herein are absent from our own solar system, making their study crucial for gaining insights into the evolutionary stages between Earth and Neptune.

The viability of organic dairy operations in the United States (US) relies on forage production. The objectives of this study were to (1) assess producer and farm information regarding current forage production practices and producer knowledge gaps and (2) identify forage research and educational needs of organic dairy producers across the US. A survey was distributed to 643 organic dairy producers across the US, with 165 respondents (26% response rate). A focus group consisting of extension professionals, university researchers and staff, consultants, dairy industry representatives and organic dairy producers was also consulted for forage research needs. Results showed that approximately half (51%) of surveyed producers were somewhat satisfied with their forage production systems and sometimes experienced negative weather-related impacts on forage yield and quality. A majority (64%) of producers felt their knowledge to meet farm goals was adequate but they reported a lack of resources to implement this knowledge especially for balancing high-forage diets and selecting soil amendments. This study revealed that 54% of producers rely on peer experiences as information resources to make decisions on forage programs. Producer knowledge gaps included pasture renovation with reduced or no-tillage, forage mixtures that match their needs, and forage management practices aiming for high-quality forage. Based on the survey and focus group findings, forage research and educational activities should foster climate change resilience regarding forage diversity adapted to local and regional climatic conditions, improve forage quality, enhance economic returns from soil fertility amendments and pasture renovation, and introduce new forages and forage mixtures that suit economical, agronomical, and environmental needs.

Laser plasma accelerators (LPAs) enable the generation of intense and short proton bunches on a micrometre scale, thus offering new experimental capabilities to research fields such as ultra-high dose rate radiobiology or material analysis. Being spectrally broadband, laser-accelerated proton bunches allow for tailored volumetric dose deposition in a sample via single bunches to excite or probe specific sample properties. The rising number of such experiments indicates a need for diagnostics providing spatially resolved characterization of dose distributions with volumes of approximately 1 cm${}^3$ for single proton bunches to allow for fast online feedback. Here we present the scintillator-based miniSCIDOM detector for online single-bunch tomographic reconstruction of dose distributions in volumes of up to approximately 1 cm${}^3$. The detector achieves a spatial resolution below 500 $\unicode{x3bc}$m and a sensitivity of 100 mGy. The detector performance is tested at a proton therapy cyclotron and an LPA proton source. The experiments’ primary focus is the characterization of the scintillator’s ionization quenching behaviour.

Laser–plasma accelerated (LPA) proton bunches are now applied for research fields ranging from ultra-high-dose-rate radiobiology to material science. Yet, the capabilities to characterize the spectrally and angularly broad LPA bunches lag behind the rapidly evolving applications. The OCTOPOD translates the angularly resolved spectral characterization of LPA proton bunches into the spatially resolved detection of the volumetric dose distribution deposited in a liquid scintillator. Up to 24 multi-pinhole arrays record projections of the scintillation light distribution and allow for tomographic reconstruction of the volumetric dose deposition pattern, from which proton spectra may be retrieved. Applying the OCTOPOD at a cyclotron, we show the reliable retrieval of various spatial dose deposition patterns and detector sensitivity over a broad dose range. Moreover, the OCTOPOD was installed at an LPA proton source, providing real-time data on proton acceleration performance and attesting the system optimal performance in the harsh laser–plasma environment.

Organic, grassfed (OGF) dairy, which requires higher pasture and forage dry matter intake compared with standard organic dairy practices, is unique both in its management needs and in production challenges. The OGF dairy sector is rapidly growing, with the expansion of this industry outpacing other dairy sectors. There is a lack of research outlining OGF dairy production practices, producer-identified research needs or social factors that affect OGF systems. The objectives of this study were to, with a group of OGF dairy producers, (1) assess information regarding current production practices and producer knowledge, and (2) identify agronomic and social factors that may influence milk production on OGF farms across the United States. A mail survey, focused on demographics, forage and animal management, knowledge, and satisfaction of their farm, was developed and distributed in 2019, with 167 responses (47% response rate). The majority of producers indicated they belonged to the plain, or Amish-Mennonite, community. Milk production was greater on farms that had Holstein cattle, as compared to farms with Jerseys and mixed breeds, and employed intensive pasture rotation. Furthermore, most producers reported the use of supplements such as molasses and kelp meal, which can improve milk production, but also increase feed costs. Producers who indicated that they were at least satisfied with their milk production also reported high levels of knowledge of grazing management and cow reproductive performance. Comparison of response data from plain/non-plain respondents revealed that those that did not identify as plain were more likely to utilize certain government programs, had different priorities and utilized technology more frequently. Based on these results, more research exploring financial and production benchmarks, effective communication strategies to reach OGF producers and methods to improve cattle production through improved forage quality is needed.

This paper considers some of the theoretical and practical problems of conducting cost-utility analyses alongside clinical trials. In order to measure utilities of different health states in a clinical trial a number of critical assumptions have to be made. Some of these assumptions are questionable on a theoretical level, others empirically invalid. The practical problems of measuring utilities are discussed. The standard gamble is shown to be the most validated method of utility measurement, but still based on very strong assumptions. The standard gamble instrument is also costly and difficult to administer in clinical trials. Other instruments are found to be less valid than the standard gamble. It is concluded that although cost-utility analysis seems relevant in some instances, investigators should avoid this assessment of utility and instead measure cost-effectiveness, cost-benefit and quality of life.

Rocks above and below the Precambrian-Palaeozoic unconformity at the base of many Palaeozoic sedimentary basins of mid-continental North America are distinguished by secondary K-feldspar, chlorite and illite. Thrusting of the Appalachian foreland is generally considered responsible for the fluid migrations which caused this alteration. We have examined secondary chlorite and illite from Cambro-Ordovician rocks which overlie the unconformity in southern Ontario, Canada. This area is situated along the interface between the Michigan and Appalachian basins. Water involved in chloritic alteration at ~150°C has an O isotope composition compatible with a basinal brine evolved from seawater. Brine migration was probably triggered by the Taconic Orogeny to the east. In comparison, the secondary illite (365–321 Ma) largely postdates the Acadian Orogeny, and the illite-forming fluids have stable isotopic compositions typical of tepid (~40–55°C) meteoric water. We suggest that basement arches beneath southern Ontario were reactivated by this orogeny, which facilitated introduction of meteoric water. Similar alteration in underlying Precambrian rocks shows that fluid flow was focused along the unconformity during the regional Ordovician brine migration, as well as during the localized Mississippian introduction of fresh water.

Extended abstract of a paper presented at Microscopy and Microanalysis 2010 in Portland, Oregon, USA, August 1 – August 5, 2010.

An agreed short text in English, French and German, presents a unified statement on those aspects of stratigraphy that require formal international acceptance. The statement is designed to avoid philosophical hazards and misunderstandings between the three language communities; it also harmonizes differences of three national traditions as far as is yet possible.

Stratigraphy is presented as an indivisible science dependent for its successful pursuit and synthesis on the application of numerous widely different methods.

The argument is presented in successive numbered steps to facilitate its critical discussion.