Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
  1. Home
  2. Search

Refine search

Refine search

Access:
Content type:
Publication date:
Apply   From and To filters
Subject: Show more
Journals Show more
Publishers: Show more
Societies Show more
Series: Show more
Collections: Show more

Actions for selected content:

Select all | Deselect all
  • View selected items
  • Export citations
  • Download PDF (zip)
  • Save to Kindle
  • Save to Dropbox
  • Save to Google Drive

Save Search

You can save your searches here and later view and run them again in "My saved searches".

Please provide a title, maximum of 40 characters.
Cancel
×

1 results

  • Structure of genetic and environmental risk factors for dimensional representations of DSM–IV anxiety disorders

  • Kristian Tambs, Nikolai Czajkowsky, Espen R⊘ysamb, Michael C. Neale, Ted Reichborn-Kjennerud, Steven H. Aggen, Jennifer R. Harris, Ragnhild E. ⊘rstavik, Kenneth S. Kendler
  • Journal:
    The British Journal of Psychiatry / Volume 195 / Issue 4 / October 2009
    Published online by Cambridge University Press:
    02 January 2018, pp. 301-307
    Print publication:
    October 2009
    • Article
      • You have access
    • PDF
    • HTML
    • Export citation
  • Background

    Twin data permit decomposition of comorbidity into genetically and environmentally derived correlations. No previous twin study includes all major forms of anxiety disorder.

    Aims

    To estimate the degree to which genetic and environmental risk factors are shared rather than unique to dimensionally scored panic disorder, generalised anxiety disorder, phobias, obsessive–compulsive disorder and post-traumatic stress disorder.

    Method

    Data obtained from 2801 young-adult Norwegian twins by means of the Composite International Diagnostic Interview were analysed with the Mx program.

    Results

    A multivariate common factor model fitted best. The latent liability to all anxiety disorders was substantially more heritable (54%) than the individual disorders (23% to 40%). Most of the genetic effect was common to the disorders. Genes contributed just over 50% to the covariance between liabilities.

    Conclusions

    The five anxiety disorders all share genetic and environmental risk factors. This has implications for the revision of the anxiety disorder section in DSM–V.