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This study examined the effectiveness of a formal postdoctoral education program designed to teach skills in clinical and translational science, using scholar publication rates as a measure of research productivity.
Participants included 70 clinical fellows who were admitted to a master’s or certificate training program in clinical and translational science from 1999 to 2015 and 70 matched control peers. The primary outcomes were the number of publications 5 years post-fellowship matriculation and time to publishing 15 peer-reviewed manuscripts post-matriculation.
Clinical and translational science program graduates published significantly more peer-reviewed manuscripts at 5 years post-matriculation (median 8 vs 5, p=0.041) and had a faster time to publication of 15 peer-reviewed manuscripts (matched hazard ratio = 2.91, p=0.002). Additionally, program graduates’ publications yielded a significantly higher average H-index (11 vs. 7, p=0.013).
These findings support the effectiveness of formal training programs in clinical and translational science by increasing academic productivity.
Pneumoperitoneum with CO2 gas begins the process of systemic acidification by altering the ultrastructural, metabolic, and immune functions of the peritoneum. Both direct and indirect effects of CO2 can be seen in numerous aspects of the cardiovascular system. Both obese and non-obese patients undergo laparoscopy at 15 mm Hg of CO2 gas in order to provide adequate visualization while minimizing the detrimental effects of increased intra-abdominal pressure (IAP). An overall decrease in renal perfusion and a resultant increase in hormonal activity occur with pneumoperitoneum. Patients with chronic obstructive pulmonary disease (COPD) often require lower IAP during laparoscopy. Effective preventions or control of detrimental effects of CO2 pneumoperitoneum are key to maintaining the safety profile of laparoscopy. Nevertheless, with the numerous benefits that stem from sequential compression devices (SCDs), their routine use has become widely recommended for all laparoscopic surgery.
Silicon carbide films have been grown on 6H-SiC (0001) and Si (001) wafers by laser ablation using an excimer laser. The films were deposited at heater plate temperatures between 970° C to 1270° C. Film composition, morphology and polytypism were determined by Auger electron spectroscopy, atomic force microscopy and high resolution transmission electron microscopy (TEM). In the course of these experiments growth of 2H-SiC on 6H-SiC was observed at the highest heater plate temperatures. Cross-sectional TEM images clearly show the symmetry of a film grown at 1270° C as c-axis oriented 2H-SiC containing columnar grains with average diameter of 20 nm and length of 100 nm.
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