Our work has focused on the fracture and fatigue crack-growth mechanisms of a Zr41.25Ti13.75Ni10Cu12.5Be22.5 bulk metallic glass. These alloys exhibit failure strengths on the order of 2 GPa and toughnesses of 10–30 MPa√m with remarkably little plastic deformation. The effect of stress state on strength properties was studied in an effort to model fracture mechanisms. While fracture surfaces suggest significant plastic flow, failure strains are quite small and appear to be independent of stress state. Other methods of energy dissipation, including adiabatic heating, are discussed. Temperature increases of more than 20°C have been noted on the side face of the fracture sample at the crack tip during fracture. The micromechanics of fatigue crack growth are also considered and related to the batch chemistry, environment, and microstructure.