To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
This chapter focuses on two specific populations of individuals often vulnerable in the conduct of research: children and prisoners. With children, prisoners, and other vulnerable populations, the challenge is to find the right balance between protection from abuse and the need to grant vulnerable populations access to participation in research. Necessary protections have two components: fair subject selection, and the specific care required to minimize wrongs to vulnerable persons once they are enrolled in research. As a group, prisoners are vulnerable due to their particular situation: being detained and therefore being deprived of the freedom to move freely. Several prison-related factors are relevant for ethical considerations about research involving prisoners. Studies designed to address health problems specific to a vulnerable population are needed to improve care for this very population, and often cannot be conducted on others.
This chapter focuses on the concept of patient consent for ansthesia for psychosurgery and electroconvulsive therapy (ECT) using the case of a 20-year-old patient with severe psychiatric disorders. Psychosurgery has a controversial history, in which medical, moral, social, and political considerations intermingle. The main ethical issues connected to these interventions involve the scientific validity of the therapy and its evaluation, the validity of patient consent, and the possibility of conflict between the interests of the patient and those of society, particularly in the case of dangerous or violent individuals. Psychosurgery raises fundamental questions, such as those linked to the definition of person and free will, concepts of dignity, integrity, and the validity of true consent. Ultimately, decisions regarding psychosurgical interventions and ECT must be made on a case-by-case basis, taking into account patient suffering and disability, and balancing these considerations with patient autonomy.