The aim of this study is to examine the influence of humble and empowering leader behaviors on the prosocial voice of subordinates. We also investigate subordinate power distance orientation as a possible moderator of this relationship and subordinate psychological empowerment as the underlying mechanism behind this moderated effect. Findings from 306 employees of a Korean business conglomerate indicated that humble and empowering leadership were positively related to the prosocial voice of subordinates, and the moderation effects of subordinates’ power distance orientation between these two types of leader behaviors and subordinates’ prosocial voice were fully mediated by the extent to which they felt psychologically empowered. Our findings indicated that the moderation for the main effect between leadership and voice was caused by the significant moderating effect in the indirect path between two main variables via psychological empowerment. We conclude by highlighting implications for management practice and identifying avenues for future research.