Dicamba may be an efficacious option for the control of glyphosate-resistant (GR) horseweed in glyphosate/dicamba-resistant soybean; research is needed to optimize the application rate based on horseweed height at the time of application. The purpose of this study was to determine the effect of glyphosate/dicamba rate and application timing for the control of GR horseweed. Glyphosate/dicamba was applied at three rates (900, 1,350, and 1,800 g ae ha−1) at three horseweed application timings (5, 15, and 25 cm) in a factorial design. There was no interaction between glyphosate/dicamba rate and timing for GR horseweed control or soybean yield; however, there was an interaction for GR horseweed density and biomass. At 2 and 4 wk after application (WAA), there was a decrease in GR horseweed control as the height at the time application increased. At 4 WAA, the application of glyphosate/dicamba to GR horseweed that was 5-, 15-, and 25-cm tall provided 87%, 76%, and 62% control, respectively. There was no impact of glyphosate/dicamba application timing on soybean yield. At 2, 4, and 8 WAA, there was an increase in GR horseweed control as the rate of glyphosate/dicamba was increased. At 8 WAA, glyphosate/dicamba applied at 900, 1,350, and 1,800 g ae ha−1 controlled GR horseweed 76%, 87%, and 92%, respectively. Earlier application timings and higher rates of glyphosate/dicamba caused the greatest reduction in GR horseweed density and biomass. Reduced GR horseweed competition resulted in a 100% to 144% increase in soybean yield, but there was no difference in soybean yield among glyphosate/dicamba rates tested.