Clustering commodity displays into a Tiled Display Wall (TDW) provides a cost-effective way to create an extremely high resolution display, capable of approaching the image sizes now generated by modern astronomical instruments. Many research institutions have constructed TDWs on the basis that they will improve the scientific outcomes of astronomical imagery. We test this concept by presenting sample images to astronomers and non-astronomers using a standard desktop display (SDD) and a TDW. These samples include standard English words, wide field galaxy surveys and nebulae mosaics from the Hubble telescope. Our experiments show that TDWs provide a better environment than SDDs for searching for small targets in large images. They also show that astronomers tend to be better at searching images for targets than non-astronomers, both groups are generally better when employing physical navigation as opposed to virtual navigation, and that the combination of two non-astronomers using a TDW rivals the experience of a single astronomer. However, there is also a large distribution in aptitude amongst the participants and the nature of the content also plays a significant role in success.