The purpose of this study was to examine regional
cerebral blood flow using positron emission tomography
(PET) during the performance of tasks related to visual
confrontation naming. Ten healthy, young participants were
scanned twice in each of 5 conditions; blood flow was measured
using standard PET [15O]-water technology.
Two major findings have replicated previous studies. First,
the naming of visually presented objects, whether covert
or overt, requires a region of the left inferior cortex
including the fusiform gyrus. Second, during overt naming,
there is an increase in activity in the inferior or frontal
cortex and insula as a consequence of generating speech
code. These data are consistent with other studies demonstrating
the importance of the inferior temporal regions for semantic
processing, and the frontal cortex for word form generation.
(JINS, 1998, 4, 160–166.)