To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure email@example.com
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Statistical models are commonly employed in the estimation of influenza-associated excess mortality that, due to various reasons, is often underestimated by laboratory-confirmed influenza deaths reported by healthcare facilities. However, methodology for timely and reliable estimation of that impact remains limited because of the delay in mortality data reporting. We explored real-time estimation of influenza-associated excess mortality by types/subtypes in each year between 2012 and 2018 in Hong Kong using linear regression models fitted to historical mortality and influenza surveillance data. We could predict that during the winter of 2017/2018, there were ~634 (95% confidence interval (CI): (190, 1033)) influenza-associated excess all-cause deaths in Hong Kong in population ⩾18 years, compared to 259 reported laboratory-confirmed deaths. We estimated that influenza was associated with substantial excess deaths in older adults, suggesting the implementation of control measures, such as administration of antivirals and vaccination, in that age group. The approach that we developed appears to provide robust real-time estimates of the impact of influenza circulation and complement surveillance data on laboratory-confirmed deaths. These results improve our understanding of the impact of influenza epidemics and provide a practical approach for a timely estimation of the mortality burden of influenza circulation during an ongoing epidemic.
Research was conducted from 2013 to 2015 across three sites in Mississippi to evaluate corn response to sublethal paraquat or fomesafen (105 and 35 g ai ha−1, respectively) applied PRE, or to corn at the V1, V3, V5, V7, or V9 growth stages. Fomesafen injury to corn at three d after treatment (DAT) ranged from 0% to 38%, and declined over time. Compared with the nontreated control (NTC), corn height 14 DAT was reduced approximately 15% due to fomesafen exposure at V5 or V7. Exposure at V1 or V7 resulted in 1,220 and 1,110 kg ha−1 yield losses, respectively, compared with the NTC, but yield losses were not observed at any other growth stage. Fomesafen exposure at any growth stage did not affect corn ear length or number of kernel rows relative to the NTC. Paraquat injury to corn ranged from 26% to 65%, depending on growth stage and evaluation interval. Corn exposure to paraquat at V3 or V5 consistently caused greater injury across evaluation intervals, compared with other growth stages. POST timings of paraquat exposure resulted in corn height reductions of 13% to 50%, except at V7, which was most likely due to rapid internode elongation at that stage. Likewise, yield loss occurred after all exposure times of paraquat except PRE, compared with the NTC. Corn yield was reduced 1,740 to 5,120 kg ha−1 compared with the NTC, generally worsening as exposure time was delayed. Paraquat exposure did not reduce corn ear length, compared with the NTC, at any growth stage. However, paraquat exposure at V3 or V5 was associated with reduction of kernel rows by 1.1 and 1.7, respectively, relative to the NTC. Paraquat and fomesafen applications near corn should be avoided if conditions are conducive for off-target movement, because significant injury and yield loss can result.
The Middle Bronze Age (c. 1600–1150 cal bc) in Britain is traditionally understood to represent a major funerary transition. This is a transformation from a heterogeneous funerary rite, largely encompassing inhumations and cremations in burial mounds and often accompanied by grave goods, to a homogeneous and unadorned cremation-based practice. Despite a huge expansion in the number of well excavated, radiocarbon dated, and osteologically analysed sites in the last three decades, current interpretations of Middle Bronze Age cremation burials still rely upon a seminal paper by Ellison (1980), which proposed that they comprise and represent an entire community. This paper analyses 378 cremation sites containing at least 3133 burials which represent all those that can be confidently dated to the Middle Bronze Age in Britain. The new analysis demonstrates that relatively few sites can be characterised as community cemeteries and that there are substantially more contemporary settlement sites, though few contemporary settlements are in close proximity to the cemeteries. The identifiable characteristics of cremation-based funerary practices are consistent across Britain with little evidence for social differentiation at the point of burial. It is also evident that only a minority of the population received a cremation burial. There is a substantial decrease in archaeologically visible funerary activity from the preceding Early Bronze Age (c. 2200–1600 cal bc) and a further decrease in the proceeding Late Bronze Age (c. 1150–800 cal bc) in Britain. This is comparable in form, and partially in sequence, to Bronze Age funerary practices in Ireland and several regions in North-west Europe.
Glyphosate-resistant (GR) Italian ryegrass is one of the most troublesome weeds in Mississippi row crop production. Fall-applied residual herbicide applications are recommended for control of GR Italian ryegrass. However, carryover of residual herbicides applied in fields for rice production can have a negative impact on rice performance. Field studies were conducted in Stoneville, MS, to determine the effects of fall-applied residual herbicides on rice growth and yield. Herbicide treatments included suggested use rates (1×) of clomazone at 840 g ai ha–1, pyroxasulfone 170 g ai ha–1, S-metolachlor 1,420 g ai ha–1, and trifluralin 1,680 g ai ha–1, and two times (2×) the suggested use rates in the fall before rice seeding. Pooled across application rate, pyroxasulfone, S-metolachlor, and trifluralin injured rice to an extent 28% to 36% greater than clomazone 14 d after emergence (DAE). Rice seedling density and height 14 DAE and rice maturity were negatively affected by all fall-applied herbicides except clomazone. Applications at 2× rates reduced rough rice yields in plots treated with pyroxasulfone, S-metolachlor, and trifluralin compared with clomazone. Pyroxasulfone applied at the 2× rate reduced rough rice yield 22% compared with the 1× rate. Rough rice yield was 90% or greater of the nontreated control in plots treated with either rate of S-metolachlor, and these were comparable with rough rice yields from plots treated with both rates of trifluralin and the 1× rate of pyroxasulfone. Early-season injury and reductions in seedling density and height 14 DAE, would preclude even 1× applications of pyroxasulfone, S-metolachlor, and trifluralin from being viable options for residual herbicide treatments targeting GR Italian ryegrass in the fall before rice seeding. Of the herbicides evaluated, only clomazone should be utilized as a fall-applied residual herbicide treatment targeting GR Italian ryegrass before seeding rice.
Accurate quantification of rates of glacier mass loss is critical for managing water resources and for assessing hazards at ice-clad volcanoes, especially in arid regions like southern Peru. In these regions, glacier and snow melt are crucial dry season water resources. In order to verify previously reported rates of ice area decline at Nevado Coropuna in Peru, which are anomalously rapid for tropical glaciers, we measured changes in ice cap area using 259 Landsat images acquired from 1980 to 2014. We find that Coropuna Ice Cap is presently the most extensive ice mass in the tropics, with an area of 44.1 km2, and has been shrinking at an average area loss rate of 0.409 km2 a−1 (~0.71% a−1) since 1980. Our estimated rate of change is considerably lower than previous studies (1.4 km2 a−1 or ~2.43% a−1), but is consistent with other tropical regions, such as the Cordillera Blanca located ~850 km to the NW (~0.68% a−1). Thus, if glacier recession continues at its present rate, our results suggest that Coropuna Ice Cap will likely continue to contribute to water supply for agricultural and domestic uses until ~2120, which is nearly 100 years longer than previously predicted.
Major efforts are being undertaken to quantify seismic hazard and risk due to production-induced earthquakes in the Groningen gas field as the basis for rational decision-making about mitigation measures. An essential element is a model to estimate surface ground motions expected at any location for each earthquake originating within the gas reservoir. Taking advantage of the excellent geological and geophysical characterisation of the field and a growing database of ground-motion recordings, models have been developed for predicting response spectral accelerations, peak ground velocity and ground-motion durations for a wide range of magnitudes. The models reflect the unique source and travel path characteristics of the Groningen earthquakes, and account for the inevitable uncertainty in extrapolating from the small observed magnitudes to potential larger events. The predictions of ground-motion amplitudes include the effects of nonlinear site response of the relatively soft near-surface deposits throughout the field.
Population-based registries report 95% 5-year survival for children undergoing surgery for CHD. This study investigated paediatric cardiac surgical outcomes in the Australian indigenous population.
All children who underwent cardiac surgery between May, 2008 and August, 2014 were studied. Demographic information including socio-economic status, diagnoses and co-morbidities, and treatment and outcome data were collected at time of surgery and at last follow-up.
A total of 1528 children with a mean age 3.4±4.6 years were studied. Among them, 123 (8.1%) children were identified as indigenous, and 52.7% (62) of indigenous patients were in the lowest third of the socio-economic index compared with 28.2% (456) of non-indigenous patients (p⩽0.001). The indigenous sample had a significantly higher Comprehensive Aristotle Complexity score (indigenous 9.4±4.2 versus non-indigenous 8.7±3.9, p=0.04). The probability of having long-term follow-up did not differ between groups (indigenous 93.8% versus non-indigenous 95.6%, p=0.17). No difference was noted in 30-day mortality (indigenous 3.2% versus non-indigenous 1.4%, p=0.13). The 6-year survival for the entire cohort was 95.9%. The Cox survival analysis demonstrated higher 6-year mortality in the indigenous group – indigenous 8.1% versus non-indigenous 5.0%; hazard ratio (HR)=2.1; 95% confidence intervals (CI): 1.1, 4.2; p=0.03. Freedom from surgical re-intervention was 79%, and was not significantly associated with the indigenous status (HR=1.4; 95% CI: 0.9, 1.9; p=0.11). When long-term survival was adjusted for the Comprehensive Aristotle Complexity score, no difference in outcomes between the populations was demonstrated (HR=1.6; 95% CI: 0.8, 3.2; p=0.19).
The indigenous population experienced higher late mortality. This apparent relationship is explained by increased patient complexity, which may reflect negative social and environmental factors.
Cultivar and/or application of early-season (starter) nitrogen (N) fertilizer may influence rice tolerance to clomazone. Field studies were conducted to compare the response of hybrid and inbred rice cultivars to applications of clomazone and starter N fertilizer treatments. The inbred cultivar ‘Cocodrie’ and the hybrid cultivar ‘XL723’ were treated with clomazone at 0, 420, or 672 g ai ha−1 immediately after seeding, and starter N fertilizer was applied at 0 or 24 kg N ha−1 when rice reached the two-leaf growth stage. Pooled across clomazone rates and starter N fertilizer treatments, height of Cocodrie 1 week after emergence (WAE) was greater than that of XL723 in 1 of 3 yr. The difference in height between Cocodrie and XL723 resulted from greater clomazone injury 1 WAE on XL723 compared with Cocodrie. No differences in rice height 3 WAE were detected between Cocodrie and XL723 in 2 of 3 yr. when data were pooled across clomazone rates and starter N fertilizer treatments. Injury 3 WAE was similar for Cocodrie across the 3 yr., but injury on XL723 was greater in 1 of 3 yr. Rough rice yield was lower in plots treated with either rate of clomazone where no starter N fertilizer treatment was applied; however, in plots receiving a starter N fertilizer treatment, no effect of clomazone rate on rough rice yield was observed. Clomazone rate did not influence rough rice yield of Cocodrie in any single yr., but rough rice yields of XL723 were lower in plots receiving clomazone compared with plots that received no clomazone in 1 of 3 yr. Therefore, differential susceptibility to clomazone between Cocodrie and XL723 exists based on early-season response and rough rice yield. Starter N fertilizer treatments were beneficial for overcoming yield reductions due to clomazone injury.
Measurements of the mechanical properties of snow are essential for improving our understanding and the prediction of snow failure and hence avalanche release. We performed fracture mechanical experiments in which a crack was initiated by a saw in a weak snow layer underlying cohesive snow slab layers. Using particle tracking velocimetry (PTV), the displacement field of the slab was determined and used to derive the mechanical energy of the system as a function of crack length. By fitting the estimates of mechanical energy to an analytical expression, we determined the slab effective elastic modulus and weak layer specific fracture energy for 80 different snowpack combinations, including persistent and nonpersistent weak snow layers. The effective elastic modulus of the slab ranged from 0.08 to 34 MPa and increased with mean slab density following a power-law relationship. The weak layer specific fracture energy ranged from 0.08 to 2.7 J m−2 and increased with overburden. While the values obtained for the effective elastic modulus of the slab agree with previously published low-frequency laboratory measurements over the entire density range, the values of the weak layer specific fracture energy are in some cases unrealistically high as they exceeded those of ice. We attribute this discrepancy to the fact that our linear elastic approach does not account for energy dissipation due to non-linear parts of the deformation in the slab and/or weak layer, which would undoubtedly decrease the amount of strain energy available for crack propagation.