Book chapters will be unavailable on Saturday 24th August between 8am-12pm BST. This is for essential maintenance which will provide improved performance going forwards. Please accept our apologies for any inconvenience caused.
To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure email@example.com
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Evidence suggests that untreated obstructive sleep apnea (OSA) is a significant health risk for the development of hypertension, cardiovascular disease, and stroke. OSA is independently associated with obesity, hypertension, and insulin resistance/diabetes mellitus, the three stroke risk factors of the metabolic syndrome. Studies in normal subjects and sleep apneic patients suggest that upper airway occlusion induces arousal from non-rapid eye movement (NREM) sleep once the level of inspiratory effort reaches a certain value, which varies among individuals. During apnea there are several stimuli that are well known to be able to induce arousal, including hypercapnia, hypoxia, and increased airway resistance. Cohort studies have shown OSA to be a risk factor for stroke. OSA is associated with a variety of stroke risk factors that may independently contribute to stroke risk. This suggests the potential for a cause-and-effect relationship between untreated OSA and stroke in some cases.
Email your librarian or administrator to recommend adding this to your organisation's collection.