Field studies were conducted in 2002 and 2003 to determine the effects of herbicides applied below suggested use rates on weed management, yield, and estimated net return of peanut in both narrow and wide row-spacing regimes. In the single row-spacing regime study, diclosulam at 6 g/ha (1/4×) (1/4 labeled use rate) plus flumioxazin at 26 g/ha (1/4×) applied PRE followed by (fb) imazapic POST at 17, (1/4×), 35, (1/2×), or 70, (1×) g/ha was the lowest herbicide input that provided at least 80% control of sicklepod, yellow nutsedge, Florida beggarweed, and hairy indigo at 21 d after treatment (DAT). By 42 DAT, weed control was ≥ 80%, similar to herbicide treatments applied at labeled rates. In the twin row-spacing regime study at Jay, FL, and Citra, FL, in 2003, yellow nutsedge control was lowest (83 to 85%) from diclosulam applied at 1/4× in combination with flumioxazin at 1/4× PRE and flumioxazin at 1/4× or 52 g/ha (1/2×) PRE alone. All other herbicide treatments provided > 90% control. Diclosulam at 13 g/ha (1/2×) fb imazapic at 1/2× and flumioxazin at 1/4× fb imazapic at 1/2× was the lowest rate combination that provided > 80% control of sicklepod. Florida beggarweed control was > 90% with all rate combinations except diclosulam PRE alone, diclosulam at 1/4× PRE fb imazapic at 1/4× POST, and imazapic at 1/4× alone POST. Net return in the single-row spacing regime was highest for flumioxazin at 105 g/ha (1×) PRE alone, diclosulam at 1/4× applied with flumioxazin at 1/4× PRE alone or fb imazapic at 1× ($1,114, $1,094, and $990/ha, respectively). The twin row-spacing regime net return was highest with diclosulam PRE alone at 1/4, 1/2, or 26 g/ha (1×) ($2,063, $1,846, $1,734/ha, respectively). Diclosulam applied with flumioxazin at 1/2× fb imazapic at 1/2× was the lowest herbicide tank-mix input providing high net return at $1,162/ha.