During several sampling periods in the Northern Adriatic Sea (Mediterranean) from 2003–2010, one species of Pista and one of Pistella were found. They were initially identified as Pista cf. lornensis (Pearson, 1969), but detailed examination revealed the presence of two new species, one belonging to the genus Pistella Hartmann-Schröder, 1996, P. rovignensis sp. nov. and one belonging to the genus Pista, P. adriatica sp. nov. These two species differ from each other in the structure of the branchiae, shape of lateral lobes and the structure of the anterior thoracic uncini. The two new species are compared with other species of Pistella and Pista currently known. The relationship of Pistella and Pista is confusing and a complete revision of the two genera is urgently needed together with other genera characterized by having long-handled thoracic uncini.