The epidemiology of notified cases of campylobacter gastroenteritis
in adults in Nottingham
Health District was investigated using a case-control study with a
postal questionnaire to
ascertain data on risk factors. Over a 14-month period 531 cases (a
73% response rate of all laboratory confirmed cases) and 512 controls replied.
Conditional logistic regression analysis was used to determine
independent associations with
infection. These included foreign travel (odds ratio (OR) 3·4; 95%
confidence intervals (CI)
2·0–5·7), diabetes mellitus (OR 4·1, CI
1·1–17), medication with omeprazole (OR 3·5, CI
and H2 and H2 antagonists (OR 3·7, CI
1·3–15), contact with puppies (OR11·3, CI1·2–105),
eating chicken (OR 1·4, CI 1·1–1·8) and drinking
milk from bottles with tops damaged by a
bird (OR 3·3, CI 1·0–11). Preparing main meals
(OR 0·9, CI 0·8–1·0) and drinking delivered
milk (OR 0·6, CI 0·4–0·9) were associated with
reduced risk of campylobacter infection.
Foreign travel was reported in 25% of cases and another 15% had
with other risk factors. The majority of cases, 60%, remained unexplained,
indicating the need for further evolution of sporadic cases.