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Skeletal muscle constitutes ~40% of total body weight, and its primary function is to provide force and energy for locomotion, breathing, and postural support. It can also act as a source of heat production during cold-induced stress or exercise. Skeletal muscle is a highly adaptable tissue that exhibits a remarkable range of plasticity in response to different stimuli. It possesses distinctive structural and biochemical properties that distinguish it from all other tissues. There is a significant variation in size, type, and shape of skeletal muscles within the body. However, the underlying morphological structure remains the same. Common to all skeletal muscle is the presence of multiple myonuclei per cell, the innervation of several cells by single α-motor neurons, and the presence of ligaments and tendons.
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