Investigating the mechanical properties and dimensional accuracy of 3D printed parts is an important step towards achieving optimum printing conditions. This condition, which leads to the fabrication of parts with appropriate mechanical properties and accuracy, is achieved by studying the effect of different process parameters on the final structure. In this work, Response Surface Methodology (RSM) was employed to design specified experiments to investigate the effects of layer thickness, printing orientation and delay, on the compressive strength and dimensional error of the parts. The results show that an increase in the delay time in X orientation results in better binder spreading and uniformity followed by improvement in the compression strength. Furthermore, more binder spreads in the vertical direction leads to the higher dimensional error in the Z direction. The results proved that the RSM provides a time and cost-efficient design to print the prototypes with optimum strength and dimensional error.