To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
Promotion of regeneration in the injured nervous system
Itzhak Fischer, Department of Neurobiology and Anatomy, Drexel University College of Medicine,
Angelo C. Lepne, Department of Neurobiology and Anatomy, Drexel University College of Medicine,
Steve Sang Woo Han, Department of Neurobiology and Anatomy, Drexel University College of Medicine,
Alan R. Tessler, Department of Neurobiology and Anatomy, Drexel University College of Medicine and Department of Veterans Affairs Hospital, Philadelphia, PA, USA
This chapter summarizes pioneering work on neural tissue transplantation that showed the feasibility of cell replacement as a treatment for spinal cord injury (SCI). It focuses on neural transplants with emphasis on the potential for neural stem cells (NSCs) and lineage-restricted precursors to replace damaged neurons and glia and to enhance regeneration. NSC has been identified not only in the fetal central nervous system (CNS), but also at later stages of CNS development and in select regions of the brain and spinal cord throughout adult life. The chapter present results of their transplantation into the spinal cord with respect to issues of fate, potential therapeutic properties and problems that need to be solved. It considers strategies for activating endogenous stem cells in the adult spinal cord for repair. Finally, the chapter reviews experimental strategies for cellular replacement in traumatic injury.
Email your librarian or administrator to recommend adding this to your organisation's collection.