In 1905, Madame Hyacinthe Loyson published her travelogue To Jerusalem through the Lands of Islam among Jews, Christians, and Moslems. In this work, Emilie Loyson, who had some experience as a journalist, described the couple’s travels in the Orient and their encounters with those of other religions, which – unusually for the time – took place on a footing of equality. This essay will first introduce the author, before turning to the religious and interreligious commitment of Emilie Loyson and her husband. Whilst in the 1870s they were engaged in ‘ecumenical’ efforts, over time their interest in interreligious encounter developed. The essay will examine – primarily from Emilie’s point of view – how the couple perceived Islam, and in particular Muslim women, as well as their understanding of Judaism and Eastern Christianity. Finally, it will ask what the couple were able to achieve.