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The Rapid ASKAP Continuum Survey (RACS) is the first large-area survey to be conducted with the full 36-antenna Australian Square Kilometre Array Pathfinder (ASKAP) telescope. RACS will provide a shallow model of the ASKAP sky that will aid the calibration of future deep ASKAP surveys. RACS will cover the whole sky visible from the ASKAP site in Western Australia and will cover the full ASKAP band of 700–1800 MHz. The RACS images are generally deeper than the existing NRAO VLA Sky Survey and Sydney University Molonglo Sky Survey radio surveys and have better spatial resolution. All RACS survey products will be public, including radio images (with
$\sim$
15 arcsec resolution) and catalogues of about three million source components with spectral index and polarisation information. In this paper, we present a description of the RACS survey and the first data release of 903 images covering the sky south of declination
$+41^\circ$
made over a 288-MHz band centred at 887.5 MHz.
The gravitationally driven flow of fluid from a reservoir following the partial collapse of its confining dam, or the partial opening of its confining lock, is modelled using the nonlinear shallow water equations, coupled to outflow conditions, in which the drainage is modelled as flow over a constricted, broad-crested weir. The resulting unsteady motion reveals systematic draining, on which strong and relatively rapid oscillations are imposed. The oscillations propagate between the outflow and the impermeable back wall of the reservoir. This dynamics is investigated utilising three methods: hodograph techniques to yield quasi-analytical solutions, asymptotic analysis at relatively late times after initiation and numerical integration of the governing equations. The hodograph transformation is used to find exact solutions at early times, revealing that from initially quiescent conditions the fluid drains and yet repeatedly generates intervals during which there are regions of constant depth and velocity adjacent to the boundaries. A novel modified multiscale asymptotic analysis designed for late times is employed to determine the limiting rate of draining and wave structure. It is shown that the excess height drains as
$t^{-2}$
and, when the obstacle has finite height, the velocity field decays as
$t^{-3}$
, and exhibits a wave structure that tends towards a constant and relatively rapid phase speed. In the case of a pure constriction, for which all the fluid ultimately drains out of the reservoir, the motion adjusts to a self-similar state in which the velocity field decays as
$t^{-1}$
. Oscillations around this state have an exponentially increasing period. Numerical simulations with a novel implementation of boundary conditions are performed; they confirm the hodograph solution and provide data for the asymptotic results.
Immune system markers may predict affective disorder treatment response, but whether an overall immune system marker predicts bipolar disorder treatment effect is unclear.
Methods:
Bipolar CHOICE (N = 482) and LiTMUS (N = 283) were similar comparative effectiveness trials treating patients with bipolar disorder for 24 weeks with four different treatment arms (standard-dose lithium, quetiapine, moderate-dose lithium plus optimised personalised treatment (OPT) and OPT without lithium). We performed secondary mixed effects linear regression analyses adjusted for age, gender, smoking and body mass index to investigate relationships between pre-treatment white blood cell (WBC) levels and clinical global impression scale (CGI) response.
Results:
Compared to participants with WBC counts of 4.5–10 × 109/l, participants with WBC < 4.5 or WBC ≥ 10 showed similar improvement within each specific treatment arm and in gender-stratified analyses.
Conclusions:
An overall immune system marker did not predict differential treatment response to four different treatment approaches for bipolar disorder all lasting 24 weeks.
Breakthrough Listen is a 10-yr initiative to search for signatures of technologies created by extraterrestrial civilisations at radio and optical wavelengths. Here, we detail the digital data recording system deployed for Breakthrough Listen observations at the 64-m aperture CSIRO Parkes Telescope in New South Wales, Australia. The recording system currently implements two modes: a dual-polarisation, 1.125-GHz bandwidth mode for single-beam observations, and a 26-input, 308-MHz bandwidth mode for the 21-cm multibeam receiver. The system is also designed to support a 3-GHz single-beam mode for the forthcoming Parkes ultra-wideband feed. In this paper, we present details of the system architecture, provide an overview of hardware and software, and present initial performance results.
The Taipan galaxy survey (hereafter simply ‘Taipan’) is a multi-object spectroscopic survey starting in 2017 that will cover 2π steradians over the southern sky (δ ≲ 10°, |b| ≳ 10°), and obtain optical spectra for about two million galaxies out to z < 0.4. Taipan will use the newly refurbished 1.2-m UK Schmidt Telescope at Siding Spring Observatory with the new TAIPAN instrument, which includes an innovative ‘Starbugs’ positioning system capable of rapidly and simultaneously deploying up to 150 spectroscopic fibres (and up to 300 with a proposed upgrade) over the 6° diameter focal plane, and a purpose-built spectrograph operating in the range from 370 to 870 nm with resolving power R ≳ 2000. The main scientific goals of Taipan are (i) to measure the distance scale of the Universe (primarily governed by the local expansion rate, H0) to 1% precision, and the growth rate of structure to 5%; (ii) to make the most extensive map yet constructed of the total mass distribution and motions in the local Universe, using peculiar velocities based on improved Fundamental Plane distances, which will enable sensitive tests of gravitational physics; and (iii) to deliver a legacy sample of low-redshift galaxies as a unique laboratory for studying galaxy evolution as a function of dark matter halo and stellar mass and environment. The final survey, which will be completed within 5 yrs, will consist of a complete magnitude-limited sample (i ⩽ 17) of about 1.2 × 106 galaxies supplemented by an extension to higher redshifts and fainter magnitudes (i ⩽ 18.1) of a luminous red galaxy sample of about 0.8 × 106 galaxies. Observations and data processing will be carried out remotely and in a fully automated way, using a purpose-built automated ‘virtual observer’ software and an automated data reduction pipeline. The Taipan survey is deliberately designed to maximise its legacy value by complementing and enhancing current and planned surveys of the southern sky at wavelengths from the optical to the radio; it will become the primary redshift and optical spectroscopic reference catalogue for the local extragalactic Universe in the southern sky for the coming decade.
The benefits of fetoscopic laser photocoagulation (FLP) for treatment of twin-to-twin transfusion syndrome (TTTS) have been recognized for over a decade, yet access to FLP remains limited in many settings. This means at a population level, the potential benefits of FLP for TTTS are far from being fully realized. In part, this is because there are many centers where the case volume is relatively low. This creates an inevitable tension; on one hand, wanting FLP to be readily accessible to all women who may need it, yet on the other, needing to ensure that a high degree of procedural competence is maintained. Some of the solutions to these apparently competing priorities may be found in novel training solutions to achieve, and maintain, procedural proficiency, and with the increased utilization of ‘competence based’ assessment and credentialing frameworks. We suggest an under-utilized approach is the development of collaborative surgical services, where pooling of personnel and resources can improve timely access to surgery, improve standardized assessment and management of TTTS, minimize the impact of the surgical learning curve, and facilitate audit, education, and research. When deciding which centers should offer laser for TTTS and how we decide, we propose some solutions from a collaborative model.
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
Scholarship in Anglo-Iberian relations developed during the second half of the twentieth and first decade of the twenty-first century to such an extent that few readers would subscribe today to the often quoted statement made in 1906 by the eminent hispanophile James Fitzmaurice-Kelly about the “almost complete insulation of each country with regard to one another” in the Middle Ages, or his other affirmation that “the first step to sustained intellectual commerce” started at the end of the fifteenth century, in allusion to the thirteen Fables of Alfonce (by the Aragonese Jewish convert, Pedro Alfonso, or Petrus Alphonsus) which were included in the 1483 edition of Caxton's Aesop. María Bullón-Fernández, among others, has also drawn our attention to this fact. Two historians in the 1950s had indeed opened the ground for new views in relation to the fourteenth century: the Spanish medievalist Luis Suárez Fernández and the Oxford scholar Peter E. Russell, although in more recent years the current interest in Al-Andalus as a decisive factor in the conformation of Europe and European culture has yielded books such as those by Jeffrey Jerome Cohen, Simon R. Doubleday and David Coleman, Sharon Kinoshita, Lisa Lampert-Weissig, or, some decades earlier, one by Alice E. Lasater.
My purpose in this chapter is not to focus on this latter sort of exploration, but rather to look back again on the particular historical, political, and dynastic conditions that linked England to Iberia during the fourteenth century, a period when writers such as John Gower, Geoffrey Chaucer, and Canciller Pero López de Ayala lived and composed their best known works.
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
Venus's dismissal of John Gower at the end of the Confessio Amantis ostensibly represents the end of his dual career as a lover and an author. Freed from his “trance” (CA VIII.2813) and shocked into recognition by the mirror rendering an accurate “liknesse of miselve” (CA VIII.2437), the poet receives a rosary of black beads with the gold inscription “Por reposer” (CA VIII.2907) and a new commission, to seek and pray for peace. This scene is echoed in the Confessio's explicit, literally the final words, in which the poet's book is sent to find lasting repose under the earl of Derby: sub eo requiesce futurus. Other elements of the poem, however, belie this sense of closure. Venus directs Gower not just to erotic and poetic retirement but to his own works: “But go ther vertu moral duelleth, | where ben thi bokes, as men telleth, | Which of long time thou has write” (CA VIII.2925–27). His literary destination is the Mirour de l'Omme and the Vox Clamantis, works that treat ethics, have found an audience influential enough to be proverbial (“as men telleth”), and were written “of long time” – both in the authoritative past and through a long process of composition and conceptual development.
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
“This is the first instalment of one of those monuments of tedious and unremunerative toil which, even in these days of commercialised literature, there are still scholars to put together, and which the Clarendon Press, to its honour, is always ready to publish.” So opens the March 1900 review in the Academy of the first volume of G. C. Macaulay's edition of John Gower's works. Volumes two and three were praised in the same periodical in 1901 as “a monument of remorseless and well-informed industry,” and the 1903 review of the Latin volume once again singles out Macaulay's “industry” and the press's “munificence,” all in service of a writer who is “tedious enough from the literary point of view, but remarkably characteristic, both in his defects and in his achievements, of the dying middle ages.” The Academy is not alone in its view: the Saturday Review closed its assessment of the Latin volume by noting that “Mr Macaulay has discharged his duty as an editor as efficiently and conscientiously as he has done in the case of the French and English poems. We heartily congratulate him on the successful completion of a work which must have involved much arduous and dreary labour.”
All these reviews set up the same dynamic. On the one hand there is Gower, writing endlessly, in three languages and, rather mysteriously it seems, enjoying such contemporary popularity that these long works normally survive in many manuscripts. On the other, there is the heroic Macaulay, weighed down by this tedious freight but doing yeoman’s service to make Gower’s works available, even though no one is likely to want to read them.
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida
Edited by
Ana Sáez-Hidalgo, Associate Professor at the University of Valladolid, Spain,R. F. Yeager, Professor of English and World Languages and chair of the department at the University of West Florida