To send content items to your account,
please confirm that you agree to abide by our usage policies.
If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account.
Find out more about sending content to .
To send content items to your Kindle, first ensure firstname.lastname@example.org
is added to your Approved Personal Document E-mail List under your Personal Document Settings
on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part
of your Kindle email address below.
Find out more about sending to your Kindle.
Note you can select to send to either the @free.kindle.com or @kindle.com variations.
‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi.
‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.
This chapter presents an interview with Vint Cerf, one of the fathers of the Internet. The chapter discusses his personal views on ethics, data and privacy, net neutrality, public policy, self-driving cars, genetic codes, and reflections on the future.
As technology becomes more powerful, intelligent, and autonomous, its usage also creates unintended consequences and ethical challenges for a vast array of stakeholders. The ethical implications of technology on society, for example, range from job losses (such as potential loss of truck driver jobs due to automation) to lying and deception about a product that may occur within a technology firm or on user-generated content platforms. The challenges around ethical technology design are so multifaceted that there is an essential need for each stakeholder to accept responsibility. Even policymakers who are charged with providing the appropriate regulatory framework and legislation about technologies have an obligation to learn about the pros and cons of proposed options.
Some of the significant features of our era include the design of large-scale systems; advances in medicine, manufacturing, and artificial intelligence (AI); the role of social media in influencing behavior and toppling governments; and the surge of online transactions that are replacing human face-to-face interactions. Most of these features have resulted from advances in technology. While spanning a variety of disciplines, these features also have two important aspects in common: the necessity for sound decision-making about the technology that is evolving, and the need to understand the ethical implications of these decisions to all stakeholders.
Many of the significant developments of our era have resulted from advances in technology, including the design of large-scale systems; advances in medicine, manufacturing, and artificial intelligence; the role of social media in influencing behaviour and toppling governments; and the surge of online transactions that are replacing human face-to-face interactions. These advances have given rise to new kinds of ethical concerns around the uses (and misuses) of technology. This collection of essays by prominent academics and technology leaders covers important ethical questions arising in modern industry, offering guidance on how to approach these dilemmas. Chapters discuss what we can learn from the ethical lapses of #MeToo, Volkswagen, and Cambridge Analytica, and highlight the common need across all applications for sound decision-making and understanding the implications for stakeholders. Technologists and general readers with no formal ethics training and specialists exploring technological applications to the field of ethics will benefit from this overview.
In the present work, mechanical, tribological, and electrochemical behaviors of Al Alloy 6061–(0–10) % B4C–(0.25–1.2) % graphene nanoplatelets (GNPs) composites, prepared by a combination of solution mixing and powder metallurgy, were investigated. Properties such as hardness, compressive strength, wear rates, and coefficient of friction (COF) were used to investigate the effects of GNPs on mechanical and self-lubricating tribological behavior. The corrosion resistance of composites was investigated using potentiodynamic polarization and electrochemical impedance techniques. Scanning electron microscopy, energy-dispersive X-ray spectroscopy (EDS), and EDS mapping were employed to study the distribution, the fracture profile, and wear mechanism. The AA 6061–10% B4C–0.6% GNPs composites exhibited sharp increase in hardness and compressive strength and significant decrease in wear rates and COF. However, for GNPs contents exceeding over 0.6 wt%, mechanical properties and wear performances deteriorated. Pulling out of sheared pultruded GNPs was observed during the fracture of composites. Worn surfaces of GNPs-containing composites showed the smeared graphene layer with some macro-cracks exhibiting delamination wear. It was found that the corrosion inhibition efficiency of GNPs was more pronounced in H3BO3 environment than in NaCl solution.
The use of streamwise finlets as a passive flow and aerodynamic noise-control technique is considered in this paper. A comprehensive experimental investigation is undertaken using a long flat plate, and results are presented for the boundary layer and surface pressure measurements for a variety of surface treatments. The pressure–velocity coherence results are also presented to gain a better understanding of the effects of the finlets on the boundary layer structures. The results show that the flow behaviour downstream of the finlets is strongly dependent on the finlet spacing. The use of finlets with coarse spacing leads to a reduction in pressure spectrum at mid- to high frequencies and an increase in spanwise length scale in the trailing-edge region due to flow channelling effects. For the finely distributed finlets, the flow is observed to behave similarly to that of a permeable backward-facing step, with significant suppression of the high-frequency pressure fluctuations but an elevation at low frequencies. Furthermore, the convection velocity is observed to reduce downstream of all finlet treatments. The trailing-edge surface pressure spectrum results have shown that, in order to obtain maximum unsteady pressure reduction, the finlet spacing should be of the order of the thickness of the inner layer of the boundary layer. A thorough study is provided for understanding of the underlying physics of both categories of finlets and their implications for controlling the flow and noise generation mechanism near the trailing edge.
Numerous studies have reported that amyloid-beta 42 (Aβ-42) protein is a high-profile risk factor associated with the onset and progression of Alzheimer’s disease (AD). Accumulation of extracellular senile plaques, synaptic degeneration, and intracellular neurofibrillary tangles were recorded as essential features that facilitate the onset of Aβ-42, resulting in AD. Hence, we attempted a new screening technique to discover potential inhibitors against Aβ-42 using an in silico deep neural network approach. We screened PubChem compounds library and found wgx-50 as a potential inhibitor of Aβ-42. Also, synergistic effects of wgx-50–gold nanoparticles (AuNPs) complex induced significant inhibition of Aβ-42, compared with those of wgx-50 alone. Further, molecular docking analysis, systems biology approach, and time course simulation confirmed that synergistic effects of wgx-50–AuNPs complex have potential application in the treatment for AD. Additionally, we proposed the biological circuit for AD induced by Aβ-42 that can be used to monitor the effect of drugs on AD.
A number field K with a ring of integers 𝒪K is called a Pólya field, if the 𝒪K-module of integer-valued polynomials on 𝒪K has a regular basis, or equivalently all its Bhargava factorial ideals are principal . We generalize Leriche's criterion  for Pólya-ness of Galois closures of pure cubic fields, to general S3-extensions of ℚ. Also, we prove for a real (resp. imaginary) Pólya S3-extension L of ℚ, at most four (resp. three) primes can be ramified. Moreover, depending on the solvability of unit norm equation over the quadratic subfield of L, we determine when these sharp upper bounds can occur.