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2 results

Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020–2022
Ralph Tayyar, Melanie A. Kiener, Jane W. Liang, Gustavo Contreras, Guillermo Rodriguez-Nava, Alex N. Zimmet, Caitlin A. Contag, Krithika Srinivasan, Karen McIntyre, Aruna Subramanian, John Shepard, Lucy S. Tompkins, Benjamin A. Pinsky, Jorge L. Salinas
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Infection Control & Hospital Epidemiology / Volume 45 / Issue 2 / February 2024

Published online by Cambridge University Press:

25 September 2023, pp. 241-243

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February 2024
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We used a strand-specific RT-qPCR to evaluate viral replication as a surrogate for infectiousness among 242 asymptomatic inpatients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test. Only 21 patients (9%) had detectable SARS-CoV-2 minus-strand RNA. Because most patients were found to be noninfectious, our findings support the suspension of asymptomatic admission testing.

Use of a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) strand-specific assay to evaluate for prolonged viral replication >20 days from illness onset
Jessica D. Ferguson, Ralph Tayyar, Gustavo Contreras, Melanie Kiener, Alex N. Zimmet, Caitlin A. Contag, Guillermo Rodriguez Nava, Lucy S. Tompkins, John Shepard, Ayelet Rosenthal, Aruna K. Subramanian, Benjamin A. Pinsky, Jorge L. Salinas
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Infection Control & Hospital Epidemiology / Volume 44 / Issue 12 / December 2023

Published online by Cambridge University Press:

29 June 2023, pp. 2078-2080

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December 2023
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Severe acute respiratory coronavirus virus 2 (SARS-CoV-2) real-time reverse-transcription polymerase chain reaction (rRT-PCR) strand-specific assay can be used to identify active SARS-CoV-2 viral replication. We describe the characteristics of 337 hospitalized patients with at least 1 minus-strand SARS-CoV-2 assay performed >20 days after illness onset. This test is a novel tool to identify high-risk hospitalized patients with prolonged SARS-CoV-2 replication.

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2 results

Low infectivity among asymptomatic patients with a positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) admission test at a tertiary care center, 2020–2022

Use of a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) strand-specific assay to evaluate for prolonged viral replication >20 days from illness onset