In organic farming the control of perennial weed species, in particular Cirsium arvense, can be a major concern for farmers, especially if there is no regulation through perennial forage production. To test whether the stubble cleaner (SC), an enhanced skim plow (PL), is as effective in the control of C. arvense and other weeds as conventional ploughing and perennial forage production, an organic field experiment was established. Three different tillage/crop rotation systems were compared: an SC system and a PL system, both in a cereal-based crop rotation and an additional PL system in a crop rotation that included a perennial alfalfa–grass mixture (PLALF). In the SC system, tillage was carried out solely with the SC, while in the PL and PLALF systems, ploughing was alternated with chiseling. In the fifth year, each main plot was divided into subplots, and seven different cover crop treatments were integrated into each of the three systems. The effects of the three systems and the cover crop treatments on weed cover and density, weed biomass, and weed diversity in the sixth and seventh year of the experiment are the subjects of this paper. The choice of cover crop species was of minor importance for weed control. The PLALF system was generally more effective in controlling C. arvense than the PL and SC systems. No significant differences between the PL and SC systems regarding the control of C. arvense could be identified in four of five assessments. The SC system had significantly higher total weed density than the PLALF and PL systems in both years. However, the differences in weed emergence between the PL and SC systems diminished until the assessment of weed cover and biomass in the main crops, when no significant differences between these two systems (2012) or no differences at all (2013) could be identified. Species richness was not significantly influenced by the tillage/crop rotation system in both years. Evenness and Shannon–Wiener index were significantly higher in the PLALF and PL systems than in the SC system on most assessment dates in 2012. In 2013 there was no clear trend regarding evenness and Shannon-Wiener index probably due to a hoeing operation.. In conclusion, for weed control, the choice of crop rotation was more important than the choice of tillage method, while for the diversity of the weed community, the choice of tillage method was more important than the crop rotation.

Analyzing votes on abortion-related legislation from the 103rd (1993–94) to the 115th (2017–18) Congresses, we find that both gender and party influence members’ voting behavior. Among Republicans, women are more likely than men to oppose pro-life initiatives, although the impact of gender attenuates over time. Among Democrats, apparent gender differences in voting behavior are explained by the nature of the districts they represent. We also find that the type of abortion issue impacts the influence of gender. Republican women are more likely than Republican men to defect on policies that highlight women's autonomy, such as on bills related to contraception, while Democratic men are more likely than Democratic women to support legislation related to abortion bans. These gender differences reflect a complex dynamic of members’ responsiveness to public opinion on specific issues and party efforts to influence that opinion in ways that favor perceptions of party issue expertise.

A design rationale is a representation of the reasoning behind a design concept, explaining why the solution is designed the way it is. This makes design rationale a critical part of concept development. However, there is little exploration on how to build a design rationale. This study sheds light on professional designers’ reasoning in conceptual design, as we examine how design rationales for different concepts are built based on a longitudinal study in the context of two design studios. Particularly the study provides insight into how a design rationale is initiated, matured and finalized.

Tuberculosis (TB) increasingly appears in a multidrug-resistant form (MDR-TB) in Europe, too. Treatment remains difficult due to various side effects of the multi-drug-regimens. Ciprofloxacin is widely used as one of the few TB-second-line drugs. We report on the course of a ciprofloxacin-induced acute psychosis in a patient with MDR(isoniazid, streptomycin)-TB which resolved after cessation of ciprofloxacin treatment and introduction of a novel oxazolidone. Careful treatment considerations particularly in patients with additional predisposing factors to neuropsychiatric symptoms are recommended in the potentially dangerous MDR-TB, thus creating an enormous therapeutic challenge.

The effect of treatment (28 days) with zopiclone, triazolam, flunitrazepam and placebo on sleep quality and daytime well-being was proven in a randomised, double-blind, parallel group, multicentre study in private practice. Results of an exploratory statistic of treatment efficacy in a subgroup of 1,291 patients suffering from insomnia are presented. Patients met the following criteria: insomnia lasting at least four weeks and the presence of at least two of the following: 1) sleep latency ≥ 45 minutes, 2) total sleep time ≤ 6 hours, and 3) nocturnal awakening ≥3 times. Treatment efficacy was assessed according to the following factors: either a shortening of sleep latency by at least 15 minutes, or prolongation of total sleep time by at least 20%, or reduction of the number of nocturnal awakenings to three or less and a refreshed feeling in the morning as well as no impairment in daytime well-being due to tiredness or anxiety. The total response rate was markedly higher with zopiclone (42.3%; p = 0.0003) than with placebo (29.0%). Triazolam (36.6%; p = 0.0905) and flunitrazepam (33.1%; p = 0.3401) were also more effective than the placebo, but they both tended to have a lower response rate than with zopiclone (p = 0.1199 and 0.0151, respectively). Total response was found to be essentially a reflection of the response of the socially important parameter of daytime well-being. These results suggest that zopiclone is more effective in the treatment of insomnia than either triazolam or flunitrazepam. Since the response of daytime well-being to therapy was generally poor, this parameter embodies the next main therapeutic challenge in the treatment of patients with insomnia.

This article presents the findings of the minimally destructive biomolecular species identification method known as ZooMS (zooarchaeology by mass spectrometry) to identify the use and choices of resources for manufacturing leather shoes in urban contexts in Viking and medieval Denmark. Whereas parchment and historical skin samples have been previously analysed by ZooMS, the potential of the method is demonstrated here for archaeological, vegetable-tanned, and waterlogged leather from the eleventh to thirteenth-century Danish cities of Ribe, Odense, and Viborg. Sheep, goat, and cattle were used to produce shoes, with explicit choices of species for specific purposes. The selection seems to be largely based on the skins’ material properties, suggesting that functionality was more important than signalling. The urban environment is seen as promoting synergy among providers of resources, crafts, and customers.

We used in-depth interviews with 101 participants in the East York section of Toronto, Canada to understand how digital media affects social connectivity in general—and networked individualism in particular—for people at different stages of the life course. Although people of all ages intertwined their use of digital media with their face-to-face interactions, younger adults used more types of digital media and have more diversified personal networks. People in different age-groups conserved media, tending to stick with the digital media they learned to use in earlier life stages. Approximately one-third of the participants were Networked Individuals: In each age-group, they were the most actively using digital media to maintain ties and to develop new ones. Another one-third were Socially Bounded, who often actively used digital media but kept their connectivity within a smaller set of social groups. The remaining one-third, who were Socially Limited, were the least likely to use digital media. Younger adults were the most likely to be Networked Individuals, leading us to wonder if the percentage of the population who are Bounded or Limited will decline over time.

Insights play a significant role in creation of new products. Insights provide the designer with an understanding of the user, market, technologies and trends, and how these might change over time. This information is critical for the designer to get an understanding of how and why present products succeed or fail. Hence, insights serve as both triggers and drivers for envisioning future products, but they are also fundamental to ensure that new products created will provide meaningful experiences to the users. In design literature, there is a significant amount of research on how to gather information about the user, market, trends, etc. However, very little research is focused on how the designer addresses this information to discover or uncover key insights. Through interviews with expert designers behind twelve products, we identified three strategies that designers use to discover insights. We found that designers search for insights that could be used to: 1) establish the product's future identity, 2) identify core challenges based on the new identity in the existing user experience and 3) identify solutions that could meet the core challenges and accentuate the new identity.

To investigate the extent of suspected hybridization between the brolga Antigone rubicunda and the Australian sarus crane Antigone antigone gillae, first noted in the 1970s, we analysed the genetic diversity of 389 feathers collected from breeding and flocking areas in north Queensland, Australia. We compared these with 15 samples from birds of known identity, or that were phenotypically typical. Bayesian clustering based on 10 microsatellite loci identified nine admixed birds, confirming that Australian cranes hybridize in the wild. Four of these were backcrosses, also confirming that wild Australian crane hybrids are fertile. Genetic analyses identified 10 times more hybrids than our accompanying visual field observations. Our analyses also provide the first definitive evidence that both brolgas and sarus cranes migrate between the Gulf Plains, the principal breeding area for sarus cranes, and major non-breeding locations on the Atherton Tablelands. We suggest that genetic analysis of shed feathers could potentially offer a cost-effective means to provide ongoing monitoring of this migration. The first observations of hybrids coincided with significantly increased opportunities for interaction between the two species when foraging on agricultural crops, which have developed significantly in the Atherton Tablelands flocking area since the 1960s. As the sarus crane is declining in much of its Asian range, challenges to the genetic integrity of the Australian sarus crane populations have international conservation significance.

In 2012, Gubeladze (Adv. Math. 2012) introduced the notion of $k$ -convex-normal polytopes to show that integral polytopes all of whose edges are longer than $4d(d+1)$ have the integer decomposition property. In the first part of this paper we show that for lattice polytopes there is no diòerence between $k$ - and $(k+1)$ -convex-normality (for $k\ge 3$ ) and improve the bound to $2d(d+1)$ . In the second part we extend the definition to pairs of polytopes. Given two rational polytopes $P$ and $\text{Q}$ , where the normal fan of $P$ is a refinement of the normal fan of $\text{Q}$ , if every edge ${{e}_{P}}$ of $P$ is at least $d$ times as long as the corresponding face (edge or vertex) ${{e}_{\text{Q}}}$ of $\text{Q}$ , then $(P+\text{Q})\cap {{\mathbb{Z}}^{d}}=(P\cap {{\mathbb{Z}}^{d}})+(\text{Q}\cap {{\mathbb{Z}}^{d}})$ .

The authors use Structural Equation Modelling techniques to analyse the determinants of wellbeing amongst older adults using data from the first wave of the Irish Longitudinal Study on Ageing (TILDA), a rich source of data on people aged over 50 and living in private households. The analysis uses a two-group linear statistical model to explore the influence of socio-economic position on the wellbeing of men and women, with Full Information Maximum Likelihood estimation to handle missing data. The fit indices for the final model are highly satisfactory and the measurement structure is invariant by gender and age. The results indicate that socio-economic position has a significant direct influence on wellbeing and a strong indirect influence which is mediated by health status and lifestyle. The total standardised effect of Socio-economic Position on Socio-emotional Wellbeing is statistically significant (p ⩽ 0.05) and equal to 0.32 (men) and 0.43 (women), a very strong influence which risks being underestimated in standard multivariate models. The authors conclude that health, cognitive functioning and wellbeing reflect not just the ageing process, but also the impact of social inequalities across the lifecourse and how they are transmitted across different life spheres. These results can help to orient future research on factors which mediate between socio-economic position and wellbeing, an important policy-related issue.

Collective entrepreneurship (CE) is the ability of several individuals to jointly innovate and create within organisations. In this exploratory study, we investigate whether the relationship between some specific leadership styles and more effective CE is affected by moderator variables. The unit of analysis were staff members of a Portuguese group of small- and medium-sized enterprises (SMEs). A total of 204 questionnaires were returned, representing almost half the employee population we approached. For measurement, we employed 19 items to gather the six latent variables related to our model. For data analysis, we used partial least squares. We found that participative leadership style had the highest joint and indirect effect on more effective CE. Job satisfaction appears to be an important moderator for the occurrence of CE. The impact of employees’ organisational commitment and collaboration on CE is rather weak. Our study contributes to advancing knowledge in the fields of organisational psychology and entrepreneurship. We combine and extend previous research, which allows us to reconcile the sometimes contradictory findings so far concerning leadership and CE in the realm of small- and medium-sized enterprises.

Objectives: Individuals with major depressive disorder (MDD) demonstrate poorer learning and memory skills relative to never-depressed comparisons (NDC). Previous studies report decreased volume and disrupted function of frontal lobes and hippocampi in MDD during memory challenge. However, it has been difficult to dissociate contributions of short-term memory and executive functioning to memory difficulties from those that might be attributable to long-term memory deficits. Methods: Adult males (MDD, n=19; NDC, n=22) and females (MDD, n=23; NDC, n=19) performed the Semantic List Learning Task (SLLT) during functional magnetic resonance imaging. The SLLT Encoding condition consists of 15 lists, each containing 14 words. After each list, a Distractor condition occurs, followed by cued Silent Rehearsal instructions. Post-scan recall and recognition were collected. Groups were compared using block (Encoding-Silent Rehearsal) and event-related (Words Recalled) models. Results: MDD displayed lower recall relative to NDC. NDC displayed greater activation in several temporal, frontal, and parietal regions, for both Encoding-Silent Rehearsal and the Words Recalled analyses. Groups also differed in activation patterns in regions of the Papez circuit in planned analyses. The majority of activation differences were not related to performance, presence of medications, presence of comorbid anxiety disorder, or decreased gray matter volume in MDD. Conclusions: Adults with MDD exhibit memory difficulties during a task designed to reduce the contribution of individual variability from short-term memory and executive functioning processes, parallel with decreased activation in memory and executive functioning circuits. Ecologically valid long-term memory tasks are imperative for uncovering neural correlates of memory performance deficits in adults with MDD. (JINS, 2016, 22, 412–425)