The 1960s and 1970s excavations at Owl Cave (10BV30) recovered mammoth bone and Folsom-like points from the same strata, suggesting evidence for a post-Clovis mammoth kill. However, a synthesis of the excavation data was never published, and the locality has since been purged from the roster of sites with human/extinct megafauna associations. Here, we present dates on bone from the oldest stratum, review provenience data, conduct a bone-surface modification study, and present the results of a protein-residue analysis. Our study fails to make the case for mammoth hunting by Folsom peoples. Although two of the point fragments tested positive for horse or elephant protein, recent AMS dates indicate that all of the mammoth remains predate Folsom, and horse remains are absent from the Owl Cave collection. Further, no unambiguously cultural surface modifications were identified on any of the mammoth remains. Given the available data, the Owl Cave deposits are most parsimoniously read as containing a Folsom-age occupation in a buried context, the first of its kind in the desert West, but one nonetheless part of a palimpsest of terminal Pleistocene materials.