Male infertility is becoming a worldwide epidemic. Data suggest that there has been a constant decline in semen parameters throughout the decades of the 20th century with the mean sperm count ranging around 60 million sperm per ml in the late 1930s and dropping down to around 40 million sperm per ml in the late 1970s [1]. More recent data from the Human Fertilisation and Embryology Authority suggests that male factor infertility is the sole cause of couple infertility in around 30% of cases and in a further 10% of cases there is a combination of male and female factors. This means that in just under one half of couples seen in a typical infertility clinic setting there will be a male factor and hence the importance of thorough investigation and management of the male partner. The exact cause for this decline in male infertility is largely unknown but may be due to various environmental factors or lifestyle changes such as smoking and obesity [2].