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Meningocele and ankyloblepharon following in utero exposure to olanzapine

Published online by Cambridge University Press:  16 April 2020

M. Arora  and
S.K. Praharaj
M. Arora*
Affiliation:
Central Institute of Psychiatry, Kanke, Ranchi 834006, Jharkhand, India
S.K. Praharaj
Affiliation:
Central Institute of Psychiatry, Kanke, Ranchi 834006, Jharkhand, India
*
*Corresponding author. Tel.: +91 651 223 2462. E-mail address: drmanu2004@rediffmail.com (M. Arora), samirpsyche@yahoo.co.in (S.K. Praharaj).
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Abstract

Although atypical antipsychotics are widely used during pregnancy, their safety is not well established. This case highlights the possible teratogenic effect of olanzapine, in which the baby was born with meningocele and ankyloblepharon. It is suggested that olanzapine may interfere with embryonic development at different stages of pregnancy.

Keywords

OlanzapineAnkyloblepharonMeningoceleTeratogenicity
Type
Short communication
Information
European Psychiatry , Volume 21 , Issue 5 , July 2006 , pp. 345 - 346
Copyright
Copyright © Elsevier SAS 2006

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