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Spermatic mitochondria: role in oxidative homeostasis, sperm function and possible tools for their assessment

  • João Diego de Agostini Losano (a1), Daniel de Souza Ramos Angrimani (a1), Roberta Ferreira Leite (a1), Bárbara do Carmo Simões da Silva (a1), Valquíria Hyppolito Barnabe (a1) and Marcilio Nichi (a1)...

Summary

Despite sperm mitochondrial relevance to the fertilization capacity, the processes involved in the production of ATP and functional dynamics of sperm mitochondria are not fully understood. One of these processes is the paradox involved between function and formation of reactive oxygen species performed by the organelle. Therefore, this review aimed to provide data on the role of sperm mitochondria in oxidative homeostasis and functionality as well the tools to assess sperm mitochondrial function.

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Corresponding author

Author for correspondence: Department of Animal Reproduction, College of Veterinary Medicine and Animal Science, University of São Paulo, Av. Prof. Orlando Marques de Paiva, 87-05508-270, São Paulo, Brazil. Tel: +55 11 30911423. Fax: +55 11 30911437. E-mail: jdalosano@usp.br

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