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Detection of glycine receptor/Cl- channel beta subunit transcripts in mouse testis

  • Yoko Sato (a1) (a2), Richard P. Tucker (a1) and Stanley Meizel (a1)


The sperm glycine receptor/Cl- channel (GlyR) is important to the initiation of the mammalian sperm acrosome reaction by the egg zona pellucida, but its presence in spermatogenic cells has not been demonstrated. Reverse transcriptase-polymerase chain reaction studies confirmed that GlyR beta subunit transcripts similar to those of the neuronal GlyR beta subunit are present in the testis of Swiss Webster mice. In situ hybridisation analysis demonstrated that GlyR beta subunit mRNAs were expressed within the germ cells of seminiferous tubules in those mice.


Corresponding author

All correspondence to: S. Meizel, Department of Cell Biology and Human Anatomy, School of Medicine, University of California at Davis, One Shields Avenue, Davis, CA 95616-8643, USA. Tel: +1 (530) 752 7108. Fax: +1 (530) 752 8520. e-mail:



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