Six substituted dinitrobenzamine herbicides, including butralin [4-(1,1-dimethylethyl)-N-(1-methylpropyl)-2,6-dinitrobenzenamine], dinitramine (N 4,N 4-diethyl-α,α,α-trifluoro-3,5-dinitrotoluene-2,4-diamine), fluchloralin [N-(2-chloroethyl)-2,6-dinitro-N-propyl-4-(trifluoromethyl)aniline], pendimethalin [N-(1-ethylpropyl)-3,4-dimethyl-2,6-dinitrobenzenamine], profluralin [N-(cyclopropylmethyl)-α,α,α-trifluoro-2,6-dinitro-N-propyl-p-toluidine], and trifluralin (α,α,α,-trifluoro-2,6-dinitro-N,N-dipropyl-p-toluidine), were evaluated as directed broadcast sprays applied and soil incorporated at time of last cultivation (layby) of cotton (Gossypium hirsutum L. ‘Acala SJ-2’). At the rates used, all herbicides provided more than 90% control of annual grasses. During 1976 and 1977, control of redroot pigweed (Amaranthus retroflexus L.) and smooth pigweed (Amaranthus hybridus L.) ranged from 90 to 100% and none of the herbicides differed significantly in their effect. However in 1975, butralin at 1.1 kg/ha did not improve pigweed control when compared to the untreated control. None of the herbicides consistently controlled black nightshade (Solanum nigrum L.) and except pendimethalin, none caused detectable cotton injury. In 2 of 3 yr, pendimethalin caused enlarged growth of the cotton stem in the cotyledonary node area contacted by the herbicide spray. Stem breakage following wind occurred in about 5% of the cotton plants; however, the injury was not manifested by reduced yield. None of the herbicides influenced cotton yield. Residues from soil samples collected 4 months after herbicide application reduced growth of Japanese millet [Echinochloa crus-galli (L.) Beauv. var. frumentacea (Link) Wright]3 and grain sorghum [Sorghum bicolor (L.) Moench] 24 to 49%.