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Project Grow-2-Gether: A Study of the Genetic and Environmental Influences on Child Eating and Obesity

  • Myles S. Faith (a1), Kathleen L. Keller (a2), Patty Matz (a3), Susan L. Johnson (a4), Rebecca Lewis (a5), Marie Alexandra Jorge (a6), Clare Ridley (a7), Helen Han (a8), Shoshanna Must (a9), Moonseong Heo (a10), Angelo Pietrobelli (a11), Steven B. Heymsfield (a12) and David B. Allison (a13)...

Abstract

“Project Grow-2-Gether” is a child nutrition study of same-sex, 3- to 7-year-old monozygotic and dizygotic twin pairs. The study attempts to bridge two bodies of literature that have rarely interfaced with respect to obesity and ingestive behavior: the first being behavioral genetic approaches to obesity-related traits, and the second being developmental approaches focusing on parent–child relationships. The overarching aim of Project Grow-2-Gether is to disentangle genetic from potential home-environmental influences on child eating behavior and body fat. This paper reviews the rationale for Project Grow-2-Gether, its procedures, and core phenotypic measurement battery. A focus of the study is acquisition of controlled food intake measurements obtained in the laboratory, measurement of specific home environmental variables, and multi-method evaluation of parent–child feeding relations. Future directions may involve longitudinal assessment of child growth and molecular analyses for specific genes that influence child eating behavior.

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Copyright

Corresponding author

*Address for correspondence: Weight and Eating Disorders Program, University of Pennsylvania School of Medicine, 3535 Market St, Third Floor, Philadelphia, PA 19104, USA.

Project Grow-2-Gether: A Study of the Genetic and Environmental Influences on Child Eating and Obesity

  • Myles S. Faith (a1), Kathleen L. Keller (a2), Patty Matz (a3), Susan L. Johnson (a4), Rebecca Lewis (a5), Marie Alexandra Jorge (a6), Clare Ridley (a7), Helen Han (a8), Shoshanna Must (a9), Moonseong Heo (a10), Angelo Pietrobelli (a11), Steven B. Heymsfield (a12) and David B. Allison (a13)...

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