Skip to main content Accessibility help
×
Home

The Mid-Atlantic Twin Registry of Virginia Commonwealth University

  • Emily C. H. Lilley (a1), Anne-Taylor Morris (a1) and Judy L. Silberg (a2)

Abstract

The Mid-Atlantic Twin Registry (MATR) is a population-based registry of more than 60,000 twins primarily born or living in Virginia, North Carolina and South Carolina. Researchers may utilize the MATR for administration of research services, including study recruitment, data or sample (e.g., DNA) collection, archival dataset creation, as well as data collection through mailed, phone or online surveys. In addition, the MATR houses the MATR Repository, with over 1700 DNA samples primarily from whole blood available for researchers interested in DNA genotyping. For over 40 years MATR twins have participated in research studies with investigators from a range of scientific disciplines and institutions. These studies, which have resulted in numerous publications, explored diverse topics, including substance use, smoking behaviors, developmental psychopathology, bullying, children’s health, cardiovascular disease, cancer, the human microbiome, epigenetics of aging, children of twins and sleep homeostasis. Researchers interested in utilizing twins are encouraged to contact the MATR to discuss potential research opportunities.

Copyright

Corresponding author

Author for correspondence: Emily C. H. Lilley, Email: echlilley@vcu.edu

References

Hide All
Anderson, L. S., Beverly, W. T., Corey, L. A., & Murelle, L. (2002). The Mid-Atlantic Twin Registry. Twin Research, 5, 449455.
Clark, S. L., McClay, J. L., Adkins, D. E., Kumar, G., Aberg, K. A., Nerella, S., … van den Oord, E. J. (2017). Deep sequencing of 71 candidate genes to characterize variation associated with alcohol dependence. Alcoholism, Clinical and Experimental Research, 41, 711718.
Do, E. K., Prom-Wormley, E. C., Eaves, L. J., Silberg, J. L., Miles, D. R., & Maes, H. H. (2018). Genetic and environmental influences on smoking behavior across adolescence and young adulthood in the Virginia Twin Study of adolescent behavioral development and the transitions to substance abuse follow-up. Twin Research and Human Genetics, 18, 4351.
Hettema, J. M., Aggen, S. H., Kubarych, T. S., Neale, M. C., & Kendler, K. S. (2015). Identification and validation of mixed anxiety-depression. Psychological Medicine, 45, 30753084.
Kendler, K. S., Gardner, C. O., Neale, M. C., Aggen, S., Heath, A., Colodro-Conde, L., … Gillespie, N. A. (2018). Shared and specific genetic risk factors for lifetime major depression, depressive symptoms and neuroticism in three population-based twin samples. Psychological Medicine, 19, 19.
Kim, S., Wyckoff, J., Morris, A.T., Succop, A., Avery, A., Duncan, G. E., & Jazwinski, S. M. (2018). DNA methylation associated with healthy aging of elderly twins. GeroScience, 40, 469484.
Kuna, S. T., Maislin, G., Pack, F. M., Staley, B., Hachadoorian, R., Coccaro, E. F., & Pack, A. I. (2012). Heritability of performance deficit accumulation during acute sleep deprivation in twins. Sleep, 35, 12231233.
Lilley, E. C., & Silberg, J. L. (2013). The Mid-Atlantic Twin Registry, revisited. Twin Research and Human Genetics, 16, 424428.
Maes, H. H., Morley, K., Neale, M. C., Kendler, K. S., Heath, A. C., Eaves, L. J., & Martin, N. G. (2018). Cross-cultural comparison of genetic and cultural transmission of smoking initiation using an extended twin kinship model. Twin Research and Human Genetics, 21, 179190.
Nichols, R. C., & Bilbro, W. C. Jr. (1966). The diagnosis of twin zygosity. Human Heredity, 16, 265275.
Rappaport, L. M., Carney, D. M., Brotman, M. A., Leibenluft, E., Pine, D. S., Roberson-Nay, R., & Hettema, J. M. (2018). A population-based twin study of childhood irritability and internalizing syndromes. Journal of Clinical Child and Adolescent Psychology, 30, 111.
Rappaport, L. M., Sheerin, C., Savage, J. E., Hettema, J. M., & Roberson-Nay, R. (2017). Clinical characteristics of latent classes of CO2 hypersensitivity in adolescents and young adults. Behaviour Research and Therapy, 93, 95103.
Sawyers, C., Oliendisk, T., Brotman, M. A., Pine, D. S., Leibenluft, E., Carney, D. M., Roberson-Nay, R., & Hettema, J. M. (2019). The genetic and environmental structure of fear and anxiety in juvenile twins. American Journal of Medical Genetics Neuropsychiatric Genetics, 180, 204212.
Silberg, J. L., Copeland, W., Linker, J., Moore, A. A., Roberson-Nay, R., & York, T. P. (2016). Psychiatric outcomes of bullying victimization: A study of discordant monozygotic twins. Psychological Medicine, 46, 18751886.
Silventoinen, K., Jelenkovic, A., Sund, R., Honda, C., Aaltonen, S., Yokoyama, Y., … Kaprio, J. (2015). The CODATwins Project: The cohort description of collaborative project of development of anthropometrical measures in twins to study macro-environmental variation in genetic and environmental effects on anthropometric traits. Twin Research and Human Genetics, 18, 348360.
Verhulst, B., Eaves, L. J., & Neale, M. C. (2014). Moderating the covariance between family member’s substance use behavior. Behavior Genetics, 44, 337346.
York, T. P., Brumelle, J., Juusola, J., Kendler, K. S., Eaves, L. J., Amstadter, A. B., … Jackson-Cook, C. (2013). Increased frequency of micronuclei in adults with a history of childhood sexual abuse: A discordant monozygotic twin study. PLoS One, 8, e55337.

Keywords

The Mid-Atlantic Twin Registry of Virginia Commonwealth University

  • Emily C. H. Lilley (a1), Anne-Taylor Morris (a1) and Judy L. Silberg (a2)

Metrics

Altmetric attention score

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed