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Late Prematurity in Twins: A Polish Multicenter Study

  • Katarzyna Kosinska-Kaczynska (a1), Iwona Szymusik (a1), Dorota Bomba-Opon (a1), Anna Madej (a1), Jan Oleszczuk (a2), Jolanta Patro-Malysza (a2), Beata Marciniak (a2), Grzegorz Breborowicz (a3), Krzysztof Drews (a4), Agnieszka Seremak-Mrozikiewicz (a4), Marta Szymankiewicz (a5), Mariusz Zimmer (a6), Michal Pomorski (a6), Anita Olejek (a7), Helena Slawska (a7) and Mirosław Wielgos (a1)...

Abstract

The study aimed at investigating the impact of late prematurity (LPT) on neonatal outcome in twins and neonatal morbidity and mortality within LPT with regard to the completed weeks of gestation. The study was conducted in six tertiary obstetric departments from different provinces of Poland (Warsaw, Lublin, Poznan, Wroclaw, Bytom). It included 465 twin deliveries in the above centers in 2012. A comparative analysis of maternal factors, the course of pregnancy and delivery and neonatal outcome between LPT (34 + 0–36 + 6 weeks of gestation) and term groups (completed 37 weeks) was performed. The neonatal outcome included short-term morbidities. The analysis of neonatal complication rates according to completed gestational weeks was carried out. Out of 465 twin deliveries 213 (44.8%) were LPT and 156 (33.55%) were term. There were no neonatal deaths among LPT and term twins. One-third of LPT newborns suffered from respiratory disorders or required antibiotics, 40% had jaundice requiring phototherapy, and 30% were admitted to NICU. The analysis of neonatal morbidity with regard to each gestational week at delivery showed that most analyzed complications occurred less frequently with the advancing gestational age, especially respiratory disorders and NICU admissions. The only two factors with significant influence on neonatal morbidity rate were neonatal birth weight (OR = 0.43, 95% CI = 0.2–0.9, p = .02) and gestational age at delivery (OR = 0.62, 95% CI = 0.5–0.8, p < .01). LPT have a higher risk of neonatal morbidity than term twins. Gestational age and neonatal birth weight seem to play a crucial role in neonatal outcome in twins.

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Copyright

Corresponding author

address for correspondence: Kosinska-Kaczynska Katarzyna, 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Starynkiewicza Square 1/3, 02-015 Warsaw, Poland. E-mail: kkaczynska@wum.edu.pl

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Keywords

Late Prematurity in Twins: A Polish Multicenter Study

  • Katarzyna Kosinska-Kaczynska (a1), Iwona Szymusik (a1), Dorota Bomba-Opon (a1), Anna Madej (a1), Jan Oleszczuk (a2), Jolanta Patro-Malysza (a2), Beata Marciniak (a2), Grzegorz Breborowicz (a3), Krzysztof Drews (a4), Agnieszka Seremak-Mrozikiewicz (a4), Marta Szymankiewicz (a5), Mariusz Zimmer (a6), Michal Pomorski (a6), Anita Olejek (a7), Helena Slawska (a7) and Mirosław Wielgos (a1)...

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