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Healthy Twin: A Twin-Family Study of Korea — Protocols and Current Status

Published online by Cambridge University Press:  21 February 2012

Joohon Sung
Affiliation:
Department of Preventive Medicine, Kangwon National University College of Medicine, Korea. ymsong@smc.samsung.co.kr
Sung-Il Cho
Affiliation:
Department of Epidemiology and Biostatistics. School of Public Health and Institute of Health and Environment, Seoul National University, Korea.
Kayoung Lee
Affiliation:
Department of Family Medicine, Busan Paik Hospital, Inje University College of Medicine, Korea.
Mina Ha
Affiliation:
Department of Preventive Medicine, Dankook University College of Medicine, Korea.
Eun-Young Choi
Affiliation:
Department of Family Medicine, Dankook University College of Medicine, Korea.
Ji-Sook Choi
Affiliation:
Center for Clinical Research, Samsung Biomedical Research Institute, Korea.
Ho Kim
Affiliation:
Department of Epidemiology and Biostatistics. School of Public Health and Institute of Health and Environment, Seoul National University, Korea.
Jihae Kim
Affiliation:
Department of Psychiatrics, Samsung Medical Center, SungKyunKwan University School of Medicine, Korea.
Kyoung Sue Hong
Affiliation:
Department of Psychiatrics, Samsung Medical Center, SungKyunKwan University School of Medicine, Korea.
Yeonju Kim
Affiliation:
Department of Preventive Medicine, Seoul National University College of Medicine, Korea.
Keun-Young Yoo
Affiliation:
Department of Preventive Medicine, Seoul National University College of Medicine, Korea.
Chan Park
Affiliation:
National Genomic Research Institute, National Institute of Health, Korea.
Yun-Mi Song*
Affiliation:
Department of Family Medicine, Samsung Medical Center, SungKyunKwan University School of Medicine, Korea. ymsong@smc.samsung.co.kr
*
*Address for correspondence: Department of Family Medicine, Samsung Medical Center, SungKyunKwan University School of Medicine, 50 Irwondong, Gangnamgu, Seoul 135–710, Korea.

Abstract

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‘Healthy Twin’ is a twin family study extension of the existing Korean Twin-Family Register. Healthy Twin recruits adult like-sex twins over the age of 30 and their adult family members. Healthy Twin protocols are primarily tailored to the study of the quantitative trait loci of complex traits as well as to the role of environment in the etiology of complex diseases. A full-length survey is underway, including questionnaires, health examinations and the collection of biological specimens. So far, 820 individuals (169 twin pairs and their families) have participated in the survey and 1068 individual twins (608 twin pairs) have replied to the mailed zygosity questionnaire as of July 2006. The first phase (2005–2006) of Healthy Twin will recruit 1550 individuals (including about 380 twin pairs), and the second phase a proposed 1500 to 2500 additional participants. We report study protocols and zygosity and the distribution of family size of the study participants.

Type
Articles/Korea
Copyright
Copyright © Cambridge University Press 2006