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Time course of regional brain activation associated with onset of auditory/verbal hallucinations

  • Ralph E. Hoffman (a1), Adam W. Anderson (a2), Maxine Varanko (a1), John C. Gore (a2) and Michelle Hampson (a3)...

Summary

The time course of brain activation prior to onset of auditory/ verbal hallucinations was characterised using functional magnetic resonance imaging in six dextral patients with schizophrenia. Composite maps of pre-hallucination periods revealed activation in the left anterior insula and in the right middle temporal gyrus, partially replicating two previous case reports, as well as deactivation in the anterior cingulate and parahippocampal gyri. These findings may reflect brain events that trigger or increase vulnerability to auditory/verbal hallucinations.

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Copyright

Corresponding author

Dr Ralph Hoffman, Yale–New Haven Psychiatric Hospital, 184 Liberty Street LV108, New Haven, CT 06519, USA. Email: ralph.hoffman@yale.edu

Footnotes

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Declaration of interest

None. Funding detailed in Acknowledgements.

Footnotes

References

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Time course of regional brain activation associated with onset of auditory/verbal hallucinations

  • Ralph E. Hoffman (a1), Adam W. Anderson (a2), Maxine Varanko (a1), John C. Gore (a2) and Michelle Hampson (a3)...
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