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Psychosocial interventions for the prevention of relapse in bipolar disorder: systematic review of controlled trials

  • Suzanne Beynon (a1), Karla Soares-Weiser (a1), Nerys Woolacott (a1), Steven Duffy (a1) and John R. Geddes (a2)...

Abstract

Background

Pharmacological interventions alone do not provide sufficient benefit for some individuals with bipolar disorder.

Aims

To determine the effectiveness of psychosocial interventions for the prevention of relapse in bipolar disorder.

Method

A systematic review and meta-analysis of randomised or quasi-randomised controlled trials were conducted.

Results

Cognitive-behavioural therapy or group psychoeducation may be effective for relapse prevention in stable individuals. Family therapy was no more or less effective than individual psychosocial therapy or crisis management. There is no evidence that care management or integrated group therapy is effective in the prevention of relapse.

Conclusions

Cognitive-behavioural therapy, group psychoeducation and possibly family therapy may be beneficial as adjuncts to pharmacological maintenance treatments.

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Copyright

Corresponding author

Nerys Woolacott, Centre for Reviews and Dissemination, University of York, York YO10 5DD, UK. Email: nw11@york.ac.uk

Footnotes

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Declaration of interest

J.G. has received research funding from Glaxo Smith Kline, Sanofi-Aventis, the UK Department of Health and Medical Research Council, the Stanley Medical Research Institute, and advisory committee payments from Bristol Myers Squibb.

Footnotes

References

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Psychosocial interventions for the prevention of relapse in bipolar disorder: systematic review of controlled trials

  • Suzanne Beynon (a1), Karla Soares-Weiser (a1), Nerys Woolacott (a1), Steven Duffy (a1) and John R. Geddes (a2)...
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eLetters

CBT: statistically significant benefit in the prevention of Bipolar disorder

Bini Rose Thomas, ST3
21 February 2008

I presented the systematic review paper in a journal club presentation in Tolworth hospital, South west London St Georges mental health trust.Although it was generally agreed that the methodology of the review was very good, the quality of the individual studies was debatable.With respect to the issue of accessibility to the services it was felt that having sound evidence supporting CBT was very helpful. Given the fact that CBT and Psycho education forms an integral part of care management it was surprising that there was not enough evidence suggesting Care management would be helpful.Although this review definitely helps clinicians to promote CBT it also does show the need for increasing research to look into the effectiveness of other interventions like family therapy and care management.S. Beynon, K. Soares-Weiser, N. Woolacott, S. Duffy, and J. R. Geddes. Psychosocial interventions for the prevention of relapse in bipolar disorder: systematic review of controlled trials.Br J Psychiatry 2008; 192: 5-11. ... More

Conflict of interest: None Declared

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