Arts, B, Jabben, N, Krabbendam, L, van Os, J. Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives. Psychol Med
2008; 38: 771–85.
Bora, E, Yucel, M, Pantelis, C. Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives. J Affect Disord
2009; 113: 1–20.
Olvet, DM, Burdick, KE, Cornblatt, BA. Assessing the potential to use neurocognition to predict who is at risk for developing bipolar disorder: a review of the literature. Cogn Neuropsychiatry
2013; 18: 129–45.
Glahn, DC, Almasy, L, Barguil, M, Hare, E, Peralta, JM, Kent, JW Jr, et al. Neurocognitive endophenotypes for bipolar disorder identified in multiplex multigenerational families. Arch Gen Psychiatry
2010; 67: 168–77.
Gourovitch, ML, Torrey, EF, Gold, JM, Randolph, C, Weinberger, DR, Goldberg, TE. Neuropsychological performance of monozygotic twins discordant for bipolar disorder. Biol Psychiatry
1999; 45: 639–46.
Kieseppa, T, Tuulio-Henriksson, A, Haukka, J, Van Erp, T, Glahn, D, Cannon, TD, et al. Memory and verbal learning functions in twins with bipolar-I disorder, and the role of information-processing speed. Psychol Med
2005; 35: 205–15.
Pirkola, T, Tuulio-Henriksson, A, Glahn, D, Kieseppa, T, Haukka, J, Kaprio, J, et al. Spatial working memory function in twins with schizophrenia and bipolar disorder. Biol Psychiatry
2005; 58: 930–6.
Christensen, MV, Kyvik, KO, Kessing, LV. Cognitive function in unaffected twins discordant for affective disorder. Psychol Med
2006; 36: 1119–29.
Kravariti, E, Schulze, K, Kane, F, Kalidindi, S, Bramon, E, Walshe, M, et al. Stroop-test interference in bipolar disorder. Br J Psychiatry
2009; 194: 285–6.
Juselius, S, Kieseppa, T, Kaprio, J, Lonnqvist, J, Tuulio-Henriksson, A. Executive functioning in twins with bipolar I disorder and healthy co-twins. Arch Clin Neuropsychol
2009; 24: 599–606.
Kravariti, E, Kane, F, Murray, RM. Neurocognitive endophenotypes for bipolar disorder: evidence from case-control, family and twin studies. In The Handbook of Neuropsychiatric Biomarkers, Endophenotypes and Genes (ed Ritsner, MS): 195–209. Springer, 2009.
Light, G, Greenwood, TA, Swerdlow, NR, Calkins, ME, Freedman, R, Green, MF, et al. Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study. Schizophr Bull
2014; 40: 1404–11.
Kendler, KS, Neale, MC. Endophenotype: a conceptual analysis. Molec Psychiatry
2010; 15: 789–97.
Tamminga, CA, Pearlson, G, Keshavan, M, Sweeney, J, Clementz, B, Thaker, G. Bipolar and schizophrenia network for intermediate phenotypes: outcomes across the psychosis continuum. Schizophr Bulletin
2014; 40 (suppl 2): S131–7.
Hall, MH, Rijsdijk, F, Picchioni, M, Schulze, K, Ettinger, U, Toulopoulou, T, et al. Substantial shared genetic influences on schizophrenia and event-related potentials. Am J Psychiatry
2007; 164: 804–12.
Schulze, KK, Walshe, M, Stahl, D, Hall, MH, Kravariti, E, Morris, R, et al. Executive functioning in familial bipolar I disorder patients and their unaffected relatives. Bipolar Disord
2011; 13: 208–16.
McDonald, C, Bullmore, ET, Sham, PC, Chitnis, X, Wickham, H, Bramon, E, et al. Association of genetic risks for schizophrenia and bipolar disorder with specific and generic brain structural endophenotypes. Arch Gen Psychiatry
2004; 61: 974–84.
World Health Organization. Schedules for Clinical Assessment in Neuropsychiatry (SCAN 2.1). WHO, 1994.
First, MB, Spitzer, RL, Gibbon, M, Williams, JBW. Structured Clinical Interview for DSM-IV Axis I Disorders – Patient Edition (With Psychotic Screen). Biometrics Research Department, 2005.
Endicott, J, Spitzer, RL. A diagnostic interview: the schedule for affective disorders and schizophrenia. Arch Gen Psychiatry
1978; 35: 837–44.
Beck, AT, Steer, RA, Brown, GK. Beck Depression Inventory Manual (2nd edn). Psychological Corporation, 1996.
Altman, EG, Hedeker, D, Peterson, JL, Davis, JM. The Altman Self-Rating Mania Scale. Soc Biol Psychiatry
1997; 42: 948–55.
Wechsler, D. Wechsler Abbreviated Scale of Intelligence (WASI). Psychological Corporation, 1999.
Delis, DC, Kramer, JH, Kaplan, E, Ober, BA. California Verbal Learning Test Manual.
Psychological Corporation, 2000.
Cambridge Cognition. Cambridge Neuropsychological Test Automated Battery Manual. Cambridge Cognition, 2004.
Rijsdijk, FV, Sham, PC. Analytic approaches to twin data using structural equation models. Brief Bioinform
2002; 3: 119–33.
Boker, SM, Neale, MC, Maes, HH, Wilde, MJ, Spiegel, M, Brick, TR, et al. OpenMx: an open source extended structural equation modeling framework. Psychometrika
2011; 76: 306–17.
Falconer, DS. The inheritance of liability to certain diseases, estimated from the incidence among relatives. Ann Hum Genet
1965; 29: 51–76.
Plomin, R. Behavioral Genetics (5th edn). Palgrave Macmillan, 2008.
McGuffin, P, Rijsdijk, F, Andrew, M, Sham, P, Katz, R, Cardno, A. The heritability of bipolar affective disorder and the genetic relationship to unipolar depression. Arch Gen Psychiatry
2003; 60: 497–502.
Sherazi, R, McKeon, P, McDonough, M, Daly, I, Kennedy, N. What's new? The clinical epidemiology of bipolar I disorder. Harv Rev Psychiatry
2006; 14: 273–84.
Rijsdijk, FV, van Haren, NE, Picchioni, MM, McDonald, C, Toulopoulou, T, Hulshoff Pol, HE, et al. Brain MRI abnormalities in schizophrenia: same genes or same environment?
2005; 35: 1399–409.
Dixon, T, Kravariti, E, Frith, C, Murray, RM, McGuire, PK. Effect of symptoms on executive function in bipolar illness. Psychol Med
2004; 34: 811–21.
Miller, GA, Chapman, JP. Misunderstanding analysis of covariance. J Abnorm Psychol
2001; 110: 40–8.
Murray, RM, Sham, P, Van Os, J, Zanelli, J, Cannon, M, McDonald, C. A developmental model for similarities and dissimilarities between schizophrenia and bipolar disorder. Schizophr Res
2004; 71: 405–16.
Fowler, T, Zammit, S, Owen, MJ, Rasmussen, F. A population-based study of shared genetic variation between premorbid IQ and psychosis among male twin pairs and sibling pairs from Sweden. Arch Gen Psychiatry
2012; 69: 460–6.
Toulopoulou, T, Goldberg, TE, Mesa, IR, Picchioni, M, Rijsdijk, F, Stahl, D, et al. Impaired intellect and memory: a missing link between genetic risk and schizophrenia?
Arch Gen Psychiatry
2010; 67: 905–13.
Krabbendam, L, Arts, B, van Os, J, Aleman, A. Cognitive functioning in patients with schizophrenia and bipolar disorder: a quantitative review. Schizophr Res
2005; 80: 137–49.
Zammit, S, Allebeck, P, David, AS, Dalman, C, Hemmingsson, T, Lundberg, I, et al. A longitudinal study of premorbid IQ Score and risk of developing schizophrenia, bipolar disorder, severe depression, and other nonaffective psychoses. Arch Gen Psychiatry
2004; 61: 354–60.
Gershon, ES, Alliey-Rodriguez, N, Liu, C. After GWAS: searching for genetic risk for schizophrenia and bipolar disorder. Am J Psychiatry
2011; 168: 253–6.
Cannon, TD, Keller, MC. Endophenotypes in the genetic analyses of mental disorders. Annu Rev Clin Psychol
2006; 2: 267–90.