Skip to main content Accessibility help
×
Home

Mitral valve prolapse and anxiety disorders

  • Alaor S. Filho (a1), Benedito C. Maciel (a2), Minna M. D. Romano (a2), Thiago F. Lascala (a2), Clarissa Trzesniak (a3), Maria C. Freitas-Ferrari (a3), Antonio E. Nardi (a4), Rocío Martín-Santos (a5), Antonio W. Zuardi (a3) and José A. S. Crippa (a3)...

Summary

We investigated whether there is an association between anxiety disorders and mitral valve prolapse. We compared mitral valve prolapse prevalence in individuals with panic disorder (n = 41), social anxiety disorder (n = 89) and in healthy controls (n = 102) in an attempt to overcome the biases of previous studies. Our results show no associations between panic disorder or social anxiety disorder and mitral valve prolapse, regardless of the diagnostic criteria employed, and that the relationship between these conditions seems not to be clinically relevant.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Mitral valve prolapse and anxiety disorders
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Mitral valve prolapse and anxiety disorders
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Mitral valve prolapse and anxiety disorders
      Available formats
      ×

Copyright

Corresponding author

José A. S. Crippa, Hospital das Clínicas – Terceiro Andar; Av. Bandeirantes, 3900; Ribeirão Preto – São Paulo, CEP – 14049-900, Brazil. Email: jcrippa@fmrp.usp.br

Footnotes

Hide All

A.W.Z. and J.A.S.C. are recipients of Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Brazil) Productivity fellowships. A.S.F. and C.T. are recipients of a CNPq (Brazil) fellowship. Research was supported in part by a grant from FundaçÃo de Apoio ao Ensino, Pesquisa e Assistência do Hospital das Clínicas da Faculdade de Medicina de Ribeirão Preto da Universidade de São Paulo (FAEPA, Brazil).

Declaration of interest

None.

Footnotes

References

Hide All
1 Margraf, J, Ehlers, A, Roth, WT. Mitral valve prolapse and panic disorder: a review of their relationship. Psychosom Med 1988; 50: 93113.
2 Filho, AS, Maciel, BC, Martín-Santos, R, Romano, MM, Crippa, JA. Does the association between mitral valve prolapse and panic disorder really exist? Prim Care Companion J Clin Psychiatry 2008; 10: 3847.
3 Chaleby, K, Ziady, G. Mitral valve prolapse and social phobia. Br J Psychiatry 1988; 152: 280–1.
4 Filho, AS, Hetem, LA, Ferrari, MC, Trzesniak, C, Martín-Santos, R, Borduqui, T, et al. Social anxiety disorder: what are we losing with the current diagnostic criteria? Acta Psychiatr Scand 2010; 121: 216–26.
5 Crippa, JA, de Lima Osório, F, Del-Ben, CM, Filho, AS, da Silva Freitas, MC, Loureiro, SR. Comparability between telephone and face-to-face structured clinical interview for DSM-IV in assessing social anxiety disorder. Perspect Psychiatr Care 2008; 44: 241–7.
6 Playford, D, Weyman, AE. Mitral valve prolapse: time for a fresh look. Rev Cardiovasc Med 2001; 2: 7381.
7 Hayek, E, Gring, CN, Griffin, BP. Mitral valve prolapse. Lancet 2005; 365: 507–18.
8 Hakim, AS, Grahame, R. A simple questionnaire to detect hypermobility: an adjunct to the assessment of patients with diffuse musculoskeletal pain. Int J Clin Pract 2003; 57: 163–6.
9 Weisse, AB. Mitral valve prolapse: now you see it; now you don't: recalling the discovery, rise and decline of a diagnosis. Am J Cardiol 2007; 99: 129–33.
10 Freed, LA, Levy, D, Levine, RA, Larson, MG, Evans, JC, Fuller, DL, et al. Prevalence and clinical outcome of mitral valve prolapse. N Engl J Med 1999; 341: 17.
Type Description Title
PDF
Supplementary materials

Filho et al. supplementary material
Supplementary Table S1

 PDF (32 KB)
32 KB

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed

Mitral valve prolapse and anxiety disorders

  • Alaor S. Filho (a1), Benedito C. Maciel (a2), Minna M. D. Romano (a2), Thiago F. Lascala (a2), Clarissa Trzesniak (a3), Maria C. Freitas-Ferrari (a3), Antonio E. Nardi (a4), Rocío Martín-Santos (a5), Antonio W. Zuardi (a3) and José A. S. Crippa (a3)...
Submit a response

eLetters

No eLetters have been published for this article.

×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *