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A Linkage Study of Primary Affective Disorder

  • Brent Waters (a1), Dharmendra Sengar (a2), Irene Marchenko (a3), Gail Rock, Yvon Lapierre (a4), Cynthia J. Forster-Gibson (a5) and Nancy E. Simpson (a5)...


Marker loci in 113 members of nine unrelated multiplex families identified by a bipolar proband were tested for linkages with primary affective disorder. Linkage was excluded between the disease locus (assuming that it was a single autosomal dominant gene) and the HLA loci at a recombination fraction of 0.2, the ABO, Rh, and Lu loci at almost 0.05 and the Fy and P loci at 0.001.


Corresponding author

Department of Child and Adolescent Psychiatry, Prince of Wales Hospital, High Street, Randwick, New South Wales 2031, Australia


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A Linkage Study of Primary Affective Disorder

  • Brent Waters (a1), Dharmendra Sengar (a2), Irene Marchenko (a3), Gail Rock, Yvon Lapierre (a4), Cynthia J. Forster-Gibson (a5) and Nancy E. Simpson (a5)...
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