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Heterogeneity of outcomes in schizophrenia: 3-year follow-up of treated prevalent cases

  • Mirella Ruggeri (a1), Antonio Lasalvia (a1), Michele Tansella (a1), Chiara Bonetto (a1), Maria Abate (a2), Graham Thornicroft (a2), Liliana Allevi (a1) and Paola Ognibene (a1)...

Abstract

Background

Care for people with schizophrenia should address a wide range of outcomes, including professional and consumer perspectives.

Aims

To measure changes in psychopathology functioning, needs for care and quality of life; to develop predictive models for each outcome domain; and to assess the frequency of ‘good'and ‘poor’ outcomes, as defined in a series of different definitions that use combinations of the four domains measured.

Method

Three-year follow-up of a 1-year-treated prevalence cohort of 107 patients with an ICD–10 diagnosis of schizophrenia attending the South Verona community-based mental health service.

Results

Mean symptom severity and some types of needs for care worsen, but quality of life shows no change. Functioning shows a non-significant trend to deteriorate. Between 32% and 42% of the variance in the four key outcomes was explained by our model. Different definitions of good'and ‘poor’ outcome included 0–31% of patients, depending on the definition used.

Conclusions

The 3-year outcome for schizophrenia depends on the domain of outcome used, whether staff or patient ratings are used and the stringency of the definitions used for good and poor outcome.

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Copyright

Corresponding author

Mirella Ruggeri, Dipartimento di Medicina e Sanitá Pubblica, Sezione di Psichiatria, Universitá di Verona, Ospedale Policlinico, 37134 Verona, Italy. Tel: +39 045 8074 441; fax: +39 045 58 58 71; e-mail: mirella.ruggeri@univr.it

Footnotes

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Declaration of interest

None. The study has been supported by a grant from Fondazione Mario Lugli (Roma).

Footnotes

References

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Heterogeneity of outcomes in schizophrenia: 3-year follow-up of treated prevalent cases

  • Mirella Ruggeri (a1), Antonio Lasalvia (a1), Michele Tansella (a1), Chiara Bonetto (a1), Maria Abate (a2), Graham Thornicroft (a2), Liliana Allevi (a1) and Paola Ognibene (a1)...
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