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A Genetic Model Compatible with a Dimensional View of Schizophrenia

Published online by Cambridge University Press:  03 January 2018

David Roberts  and
Gordon Claridge
David Roberts*
Affiliation:
Genetics Laboratory, Department of Biochemistry, Oxford University
Gordon Claridge
Affiliation:
Department of Experimental Psychology, Oxford University
*
∗Genetics Laboratory, Department of Biochemistry, South Parks Road, Oxford OX1 3QU
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Extract

Throughout the history of schizophrenia as a psychiatric concept, opinions have differed sharply over its essential nature and its causes, giving rise to a wide range of explanations that have drawn upon ideas from almost all of the social and biological sciences. Only one fact has truly survived the vicissitudes of argument about the condition: that genetic factors contribute to its aetiology. Even that conclusion, first reached in the very early days of schizophrenia research, sank temporarily out of sight during the radical psychiatry challenges of the 1960s. However, the continuing collection of family, twin, adoption and other data over that period put the genetic hypothesis beyond reasonable doubt (McGuffin, 1988).

Type
Annotation
Information
The British Journal of Psychiatry , Volume 158 , Issue 4 , April 1991 , pp. 451 - 456
Copyright
Copyright © Royal College of Psychiatrists, 1991 

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