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The Dexamethasone Suppression Test and Suicidal Patients

  • Jon Ennis (a1), Rosemary A. Barnes (a1) and Sidney Kennedy (a1)

Abstract

The dexamethasone suppression test (DST) was used in an in-patient crisis unit to determine whether the test could identify suicidal patients who might benefit from tricyclic antidepressants. DST results, DSM-III diagnoses, and measures of symptom levels were obtained for 72 patients admitted for a 3–5 day period; 31 were non-suppressors. Abnormal DST results were not related to DSM-III diagnosis or to scores on measures of depression and symptom levels. Only three patients met DSM-III criteria for major depression with melancholia; 26 patients had a diagnosis of alcohol or substance abuse. The poor specificity of the DST in this patient population suggests that its routine use in such patients could be highly misleading.

Copyright

Corresponding author

Dr. Jon Ennis, Department of Psychiatry, Toronto General Hospital, Eaton Building, Eighth Floor, 101 College Street, Toronto, Ontario, M5G 1L7, Canada

References

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The British Journal of Psychiatry
  • ISSN: 0007-1250
  • EISSN: 1472-1465
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The Dexamethasone Suppression Test and Suicidal Patients

  • Jon Ennis (a1), Rosemary A. Barnes (a1) and Sidney Kennedy (a1)
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