Hostname: page-component-8448b6f56d-c4f8m Total loading time: 0 Render date: 2024-04-16T16:08:20.760Z Has data issue: false hasContentIssue false
  • English
  • Français

Commentary on: Randomised, double-blind, placebo-controlled trial of fluoxetine and graded exercise for chronic fatigue syndrome†

Published online by Cambridge University Press:  03 January 2018

Alicia Deale ,
Trudie Chalder  and
Simon Wessely
Alicia Deale*
Affiliation:
Department of Psychological Medicine, King's College Hospital
Trudie Chalder
Affiliation:
Academic Department of Psychological Medicine, King's College School of Medicine and Dentistry, and Institute of Psychiatry
Simon Wessely
Affiliation:
Academic Department of Psychological Medicine, King's College School of Medicine and Dentistry, and Institute of Psychiatry
*
Alicia Deale, Department of Psychological Medicine, King's College Hospital, Denmark Hill, London SES 9RS
Get access Rights & Permissions [Opens in a new window]

Extract

A variety of treatments for chronic fatigue syndrome (CFS) have been proposed but few have been systematically evaluated. The publication of this well-designed, double-blind, randomised controlled trial is therefore a welcome contribution to the literature.

Type
Papers
Information
The British Journal of Psychiatry , Volume 172 , Issue 6 , June 1998 , pp. 491 - 492
Copyright
Copyright © 1998 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Footnotes

†.

See pp. 485–490, this issue.

References

Deale, A. Chalder, T. Marks, I. et al (1997) Cognitive behaviour therapy for chronic fatigue syndrome: a randomised controlled trial. American Journal of Psychiatry, 154, 408–414.Google Scholar
Deale, A. Chalder, T. & Wessely, S. (1998) Illness beliefs and treatment outcome in chronic fatigue syndrome. Journal of Psychosomatic Research, in press.CrossRefGoogle Scholar
Friedberg, F. & Krupp, L. (1994) A comparison of cognitive–behavioural treatment for chronic fatigue syndrome and primary depression. Clinical Infectious Diseases, 18 (suppl. 1). s105–s110.CrossRefGoogle Scholar
Fulcher, K. & White, P. (1997) Randomised controlled trial of graded exercise in patients with the chronic fatigue syndrome. British Medical Journal, 314, 1647–1652.CrossRefGoogle ScholarPubMed
Hickie, I. Wilson, A. Wright, J. et al (1998) A randomised, double-blind, placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome. British Journal of Psychiatry, in press.Google Scholar
Hollon, S. & De Rubeis, R. (1981) Placebo-therapy combinations: inappropriate representations of psychotherapy in drug-psychotherapy comparative trials. Psychological Bulletin, 90, 467–477.CrossRefGoogle Scholar
Lloyd, A. Hickie, I. Brockman, A. et al (1993) Immunologic and psychologic therapy for patients with chronic fatigue syndrome: a double blind, placebo controlled trial. American Journal of Medicine, 94, 197–203.CrossRefGoogle ScholarPubMed
Lonnqvist, J. Sihvo, S. Syvakahti, E. et al (1994) Moclobemide and fluoxetine in atypical depression: a double blind trial. Journal of Affective Disorders, 32, 169–177.CrossRefGoogle ScholarPubMed
McCully, K. Sisto, S. & Nataljon, B. (1996) Use of exercise for the treatment of chronic fatigue syndrome. Sports Medicine, 21, 35–45.CrossRefGoogle ScholarPubMed
Natelson, B. Chen, J. Pareja, J. et al (1996) Randomised, double blind controlled placebo phase in trial of low dose phenelzine in the chronic fatigue syndrome. Psychopharmacology, 124, 226–230.CrossRefGoogle ScholarPubMed
Norregaard, J. Volkman, H. & Danneskiold Samsoe, B. (1995) A randomised controlled trial of citalopram in the treatment of fibromyalgia, Pain, 61, 445–449.CrossRefGoogle ScholarPubMed
Sharpe, M. Hawton, K. Simkin, S. et al (1996) Cognitive behaviour therapy for the chronic fatigue syndrome: a randomised controlled trial. British Medical Journal, 312, 22–26.CrossRefGoogle Scholar
Vercoulen, J. Swanink, C. Sitman, F. et al (1996) Randomised double-blind placebo controlled study of fluoxetine in chronic fatigue syndrome. Lancet, 347, 858–861.CrossRefGoogle ScholarPubMed
Wearden, A. J. Morriss, R. K. Mullis, R. et al (1998) Randomised, double-blind, placebo-controlled trial of fluoxetine and graded exercise for chronic fatugue syndrome. British Journal of Psychiatry, 172, 485–490.CrossRefGoogle ScholarPubMed
Wessely, S. Hotopf, M. & Sharpe, M. (1998) Chronic Fatigue and its Syndromes. Oxford: Oxford University Press.CrossRefGoogle Scholar
Wolfe, F. Cathey, M. & Hawley, D. (1994) A double-blind placebo controlled trial of fluoxetine in fibromyalgia. Scandinavian Journal of Rheumatology, 23, 255–259.CrossRefGoogle ScholarPubMed
Submit a response

eLetters

No eLetters have been published for this article.